Global Patent Index - EP 0782582 A1

EP 0782582 A1 19970709 - EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5-g(a)-ANDROST-1-ENE-17-g(b)-CARBOXAMIDE

Title (en)

EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5-g(a)-ANDROST-1-ENE-17-g(b)-CARBOXAMIDE

Title (de)

EPIMER VON (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5-ALPHA-ANDROST-1-ENE-17-BETA-CARBOXAMIDE

Title (fr)

EPIMERES DE (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-Y-YL)-3-OXO-4-AZA-5-g(a)-ANDROST-1-ENE-17-g(b)-CARBOXAMIDE

Publication

EP 0782582 A1 19970709 (EN)

Application

EP 96923968 A 19960628

Priority

  • EP 9602830 W 19960628
  • IT MI951587 A 19950721

Abstract (en)

[origin: WO9704002A1] The present invention relates to the epimers: (22R)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5 alpha -androst-1-ene-17 beta -carboxamide and (22S)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-oxo-4-aza-5 alpha -androst-1-ene-17 beta -carboxamide useful as inhibitors of testosterone 5 alpha -reductase enzyme, to a process for their preparation and to pharmaceutical compositions containing them.

IPC 1-7

C07J 73/00; A61K 31/58

IPC 8 full level

A61P 43/00 (2006.01); C07J 73/00 (2006.01); A61K 31/58 (2006.01)

CPC (source: EP KR)

A61K 31/58 (2013.01 - KR); A61P 43/00 (2018.01 - EP); C07J 73/00 (2013.01 - KR); C07J 73/005 (2013.01 - EP)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE

DOCDB simple family (publication)

WO 9704002 A1 19970206; AR 003967 A1 19980930; AU 6418396 A 19970218; BR 9606527 A 19971223; CA 2199273 A1 19970206; CN 1159195 A 19970910; EA 199700045 A1 19971230; EP 0782582 A1 19970709; HU P9702465 A2 19980528; HU P9702465 A3 19981130; IL 120343 A0 19970610; IT 1275594 B1 19970806; IT MI951587 A0 19950721; IT MI951587 A1 19970121; JP H10506411 A 19980623; KR 970706298 A 19971103; MX 9701948 A 19970628; NO 971196 D0 19970314; NO 971196 L 19970314; PL 319351 A1 19970804; ZA 965678 B 19970124

DOCDB simple family (application)

EP 9602830 W 19960628; AR 10365296 A 19960719; AU 6418396 A 19960628; BR 9606527 A 19960628; CA 2199273 A 19960628; CN 96190785 A 19960628; EA 199700045 A 19970418; EP 96923968 A 19960628; HU P9702465 A 19960628; IL 12034396 A 19960628; IT MI951587 A 19950721; JP 50621797 A 19960628; KR 19970701797 A 19970320; MX 9701948 A 19960628; NO 971196 A 19970314; PL 31935196 A 19960628; ZA 965678 A 19960704