EP 0783508 A1 19970716 - THE OLIGOSACCHARIDE STRUCTURE OF A LIGAND FOR E AND P SELECTIN
Title (en)
THE OLIGOSACCHARIDE STRUCTURE OF A LIGAND FOR E AND P SELECTIN
Title (de)
OLIGOSACCHARIDSTRUKTUR AUF EINEM LIGAND FÜR E UND P SELECTIN
Title (fr)
STRUCTURE OLIGOSACCHARIDE D'UN LIGAND DE LA SELECTINE E ET P
Publication
Application
Priority
- US 9511401 W 19950915
- US 30901294 A 19940920
- US 43329895 A 19950503
Abstract (en)
[origin: WO9609309A1] A specific ligand for E- and P-selectin was isolated from in vivo[<3>H]-glucosamine labeled HL-60 cells by a combination of weat germ agglutinin agarose and E- or P-selectin rIg-agarose chromatography. The total O-linked oligosaccharides on the purified molecule were released by alkaline hydrolysis in the presence of NaBH4 and analyzed by ion-exchange, size-exclusion and paper chromatography in combination with specific exoglycosidase digestions. Various derived ligands and carbohydrates are claimed.
IPC 1-7
IPC 8 full level
A61K 31/70 (2006.01); A61K 31/702 (2006.01); A61K 31/7024 (2006.01); A61P 7/02 (2006.01); A61P 9/00 (2006.01); A61P 11/00 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07H 3/06 (2006.01); C07H 13/06 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); A61P 9/00 (2017.12); A61P 11/00 (2017.12); A61P 13/02 (2017.12); A61P 15/00 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C07H 3/06 (2013.01)
Citation (search report)
See references of WO 9609309A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9609309 A1 19960328; AU 3548695 A 19960409; EP 0783508 A1 19970716; JP H10508580 A 19980825
DOCDB simple family (application)
US 9511401 W 19950915; AU 3548695 A 19950915; EP 95932441 A 19950915; JP 51093496 A 19950915