EP 0783516 A1 19970716 - PHOSPHORUS-32 LABELING OF ANTIBODIES FOR CANCER THERAPY
Title (en)
PHOSPHORUS-32 LABELING OF ANTIBODIES FOR CANCER THERAPY
Title (de)
DIE MARKIERUNG VON ANTIKÖRPERN FÜR DIE KREBSBEHANDLUNG MIT PHOSPHOR-32
Title (fr)
MARQUAGE DES ANTICORPS AU PHOSPHORE 32 POUR LE TRAITEMENT DU CANCER
Publication
Application
Priority
- US 9511405 W 19950918
- US 30810394 A 19940916
Abstract (en)
[origin: WO9608506A1] Recombinant fusion proteins containing at least one domain which confers targeting properties on the fusion protein, together with at least one peptide sequence that is a substrate for a protein kinase, can be labeled with <32>P or <33>P by treatment with a protein kinase and a <32>P- or <33>P-labeled phosphate donor. The labeled targeting proteins bind specifically to diseased cells or tissue, which are killed by the radiation from the <32>P or <33>P.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 51/00 (2006.01); C07K 1/13 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/54 (2006.01); C07K 16/30 (2006.01); C07K 19/00 (2006.01); C12P 21/02 (2006.01); C12R 1/19 (2006.01)
CPC (source: EP)
C07K 1/13 (2013.01); C07K 14/5412 (2013.01); C07K 16/30 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9608506 A1 19960321; AU 3548895 A 19960329; CA 2200088 A1 19960321; EP 0783516 A1 19970716; EP 0783516 A4 19990915; IL 115177 A0 19951231; JP H10511263 A 19981104
DOCDB simple family (application)
US 9511405 W 19950918; AU 3548895 A 19950918; CA 2200088 A 19950918; EP 95932443 A 19950918; IL 11517795 A 19950905; JP 51025496 A 19950918