Global Patent Index - EP 0784478 A1

EP 0784478 A1 19970723 - INHIBITION OF ENDOTHELIN-1 TO REDUCE INFLAMMATORY PROCESSES

Title (en)

INHIBITION OF ENDOTHELIN-1 TO REDUCE INFLAMMATORY PROCESSES

Title (de)

HEMMUNG VON ENDOTHELIN-1 ZUR REDUZIERUNG VON ENTZÜNDLICHEN PROZESSEN

Title (fr)

INHIBITION DE L'ENDOTHELINE-1 POUR COMBATTRE LES INFLAMMATIONS

Publication

EP 0784478 A1 19970723 (EN)

Application

EP 95933865 A 19950912

Priority

  • US 9511937 W 19950912
  • US 30735494 A 19940914

Abstract (en)

[origin: WO9608268A1] The vasoactive and mitogenic peptide, endothelin-1 (ET-1) is upregulated within grafts, and methods of diagnosing and treating graft rejection, arteriosclerosis, and other cell-mediated inflammatory conditions are provided. These methods involve identifying and reducing expression of ET-1.

IPC 1-7

A61K 38/12; A61K 48/00; C12N 15/12

IPC 8 full level

G01N 33/50 (2006.01); A61K 38/00 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61K 49/00 (2006.01); A61P 37/06 (2006.01); A61P 43/00 (2006.01); C07K 14/575 (2006.01); C07K 14/72 (2006.01); C07K 16/28 (2006.01); C12N 15/12 (2006.01); G01N 33/15 (2006.01); G01N 33/53 (2006.01)

CPC (source: EP)

A61P 37/06 (2017.12); A61P 43/00 (2017.12); C07K 14/57536 (2013.01); C07K 14/723 (2013.01); C07K 16/2869 (2013.01); G01N 33/5088 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); G01N 2333/5754 (2013.01); G01N 2800/245 (2013.01)

Citation (search report)

See references of WO 9608268A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9608268 A1 19960321; CA 2199939 A1 19960321; EP 0784478 A1 19970723; JP H10508830 A 19980902

DOCDB simple family (application)

US 9511937 W 19950912; CA 2199939 A 19950912; EP 95933865 A 19950912; JP 51040496 A 19950912