Global Patent Index - EP 0784672 A4

EP 0784672 A4 19990317 - HUMAN INOSITOL MONOPHOSPHATASE H1

Title (en)

HUMAN INOSITOL MONOPHOSPHATASE H1

Title (de)

MENSCHLICHE INOSITOL MONOPHOSPHATASE H1

Title (fr)

INOSITOL MONOPHOSPHATASE H1 HUMAINE

Publication

EP 0784672 A4 19990317 (EN)

Application

EP 94930440 A 19940916

Priority

US 9410465 W 19940916

Abstract (en)

[origin: WO9608557A1] Human inositol monophosphatase H1 polynucleotide and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptide by recombinant techniques and utilizing such polypeptide for therapeutic purposes, for example, screening and designing compounds capable of inhibiting hIMP-H1 and mapping genetic diseases are disclosed. Also disclosed are antagonists against such polypeptide along with procedures for using such antagonists for therapeutic purposes, for example, for treating psychotic and depressive disorders.

IPC 1-7

C12N 1/21; C12N 5/10; C12N 9/16; C12N 15/55; C12N 15/63; C12N 15/64

IPC 8 full level

C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); A61P 25/24 (2006.01); A61P 25/26 (2006.01); A61P 43/00 (2006.01); C07K 16/18 (2006.01); C12N 5/00 (2006.01); C12N 5/10 (2006.01); C12N 9/16 (2006.01); C12N 15/55 (2006.01); C12Q 1/42 (2006.01); C12R 1/19 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP)

A61P 13/02 (2017.12); A61P 15/00 (2017.12); A61P 25/24 (2017.12); A61P 25/26 (2017.12); A61P 43/00 (2017.12); C12N 9/16 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [XD] WO 9325692 A1 19931223 - MERCK SHARP & DOHME [GB], et al
  • [X] EP 0485026 A2 19920513 - MERCK SHARP & DOHME [GB]
  • [A] BONE R. ET AL.: "Structure of inositol monophosphatase, the putative target of lithium therapy", PNAS,U.S.A., vol. 89, no. 21, 1 November 1992 (1992-11-01), pages 10031 - 10035, XP002089705
  • See references of WO 9608557A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9608557 A1 19960321; AU 7956494 A 19960329; EP 0784672 A1 19970723; EP 0784672 A4 19990317; JP H10505747 A 19980609

DOCDB simple family (application)

US 9410465 W 19940916; AU 7956494 A 19940916; EP 94930440 A 19940916; JP 51013796 A 19940916