EP 0787187 A1 19970806 - HER4 HUMAN RECEPTOR TYROSINE KINASE
Title (en)
HER4 HUMAN RECEPTOR TYROSINE KINASE
Title (de)
HER4-MENSLICHER REZEPTOR TYROSINE KINASE VON DER EPIDERMALEN WACHSTUMSFAKTOR REZEPTOR FAMILIE
Title (fr)
RECEPTEUR HUMAIN HER4 A ACTIVITE TYROSINE-KINASE
Publication
Application
Priority
- US 9513524 W 19951010
- US 32344294 A 19941014
Abstract (en)
[origin: WO9612019A2] The molecular cloning, expression, and biological characteristics of a novel receptor tyrosine kinase related to the epidermal growth factor receptor, termed HER4/p180<erbB4>, are described. An HER4 ligand capable of inducing cellular differentiation of breast cancer cells is also disclosed. In view of the expression of HER4 in several human cancers and in certain tissues of neuronal and muscular origin, various diagnostic and therapeutic uses of HER4-derived and HER4-related biological compositions are provided.
IPC 1-7
C12N 15/12; C07K 14/71; C07K 16/28; C07K 14/47; C12N 15/62; G01N 33/68
IPC 8 full level
A61K 47/48 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 14/47 (2006.01); C07K 14/475 (2006.01); C07K 14/485 (2006.01); C07K 14/71 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12N 15/87 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
A61K 47/6425 (2017.07); A61K 47/6849 (2017.07); C07K 14/4756 (2013.01); C07K 14/485 (2013.01); C07K 14/71 (2013.01); C07K 16/2863 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); G01N 2333/4756 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9612019 A2 19960425; WO 9612019 A3 19960815; AU 3963295 A 19960506; CA 2202533 A1 19960425; EP 0787187 A1 19970806; FI 971532 A0 19970411; FI 971532 A 19970611; IL 115642 A0 19960119; JP H10507362 A 19980721; MX 9702664 A 19970628; NO 971686 D0 19970411; NO 971686 L 19970616
DOCDB simple family (application)
US 9513524 W 19951010; AU 3963295 A 19951010; CA 2202533 A 19951010; EP 95937555 A 19951010; FI 971532 A 19970411; IL 11564295 A 19951015; JP 51346996 A 19951010; MX 9702664 A 19951010; NO 971686 A 19970411