Global Patent Index - EP 0788557 A4

EP 0788557 A4 20030806 - RAPID DETECTION AND IDENTIFICATION OF NUCLEIC ACID VARIANTS AND PATHOGENS

Title (en)

RAPID DETECTION AND IDENTIFICATION OF NUCLEIC ACID VARIANTS AND PATHOGENS

Title (de)

SCHNELLER NACHWEIS UND IDENTIFIZIERUNG VON NUKLEINSÄURE VARIANTEN UND PATHOGENEN

Title (fr)

DETECTION ET IDENTIFICATION RAPIDES DE VARIANTS DE L'ACIDE NUCLEIQUE ET D'AGENTS PATHOGENES

Publication

EP 0788557 A4 20030806 (EN)

Application

EP 95940678 A 19951109

Priority

  • US 9514673 W 19951109
  • US 33716494 A 19941109
  • US 40260195 A 19950309
  • US 48495695 A 19950607
  • US 52094695 A 19950830

Abstract (en)

[origin: WO9615267A1] The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5' nucleases and 3' exonucleases, are used to screen for known and unknown mutations, including single base changes, in nucleic acids. Methods are provided which allow for the identification of genetic mutations in human gene sequences, including the human p53 gene, in a sample. Methods are provided which allow for the detection and identification of bacterial and viral pathogens and species in a sample.

IPC 1-7

C12Q 1/68; C12Q 1/70; C12P 19/34; C12N 9/22; A61K 38/47; G01N 27/26; C07H 21/02; C12N 9/12

IPC 8 full level

G01N 33/50 (2006.01); A61K 38/47 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07K 14/47 (2006.01); C07K 14/82 (2006.01); C12N 9/16 (2006.01); C12N 9/22 (2006.01); C12N 15/09 (2006.01); C12N 15/10 (2006.01); C12P 19/34 (2006.01); C12Q 1/04 (2006.01); C12Q 1/68 (2006.01); C12Q 1/70 (2006.01); G01N 27/26 (2006.01)

CPC (source: EP)

C07H 21/00 (2013.01); C07K 14/4746 (2013.01); C07K 14/82 (2013.01); C12N 9/22 (2013.01); C12N 15/10 (2013.01); C12Q 1/683 (2013.01)

Citation (search report)

  • [X] EP 0601834 A1 19940615 - WISCONSIN ALUMNI RES FOUND [US]
  • [X] WO 9202638 A1 19920220 - CETUS CORP [US]
  • [A] WO 9200311 A1 19920109 - UNIV PRINCETON [US]
  • [LPX] WO 9429482 A1 19941222 - THIRD WAVE TECH INC [US]
  • [X] LYAMICHEV V ET AL: "STRUCTURE-SPECIFIC ENDONUCLEOLYTIC CLEAVAGE OF NUCLEIC ACIDS BY EUBACTERIAL DNA POLYMERASES", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 260, 7 May 1993 (1993-05-07), pages 778 - 783, XP002910110, ISSN: 0036-8075
  • [X] HARRINGTON J J ET AL: "THE CHARACTERIZATION OF A MAMMALIAN DNA STRUCTURE-SPECIFIC ENDONUCLEASE", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 13, no. 5, 1 March 1994 (1994-03-01), pages 1235 - 1246, XP002121673, ISSN: 0261-4189
  • See references of WO 9615267A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9615267 A1 19960523; AU 4234796 A 19960606; AU 4444699 A 19991014; CA 2203627 A1 19960523; CA 2203627 C 20000606; EP 0788557 A1 19970813; EP 0788557 A4 20030806; JP H10509322 A 19980914

DOCDB simple family (application)

US 9514673 W 19951109; AU 4234796 A 19951109; AU 4444699 A 19990812; CA 2203627 A 19951109; EP 95940678 A 19951109; JP 51622796 A 19951109