EP 0789768 A1 19970820 - RESPIRATORY SYNCYTIAL VIRUS PROTEIN G EXPRESSED ON BACTERIAL MEMBRANE
Title (en)
RESPIRATORY SYNCYTIAL VIRUS PROTEIN G EXPRESSED ON BACTERIAL MEMBRANE
Title (de)
PROTEIN G VON RESPIRATORY SYNCITIAL VIRUS, EXPRIMIERT AUF BAKTERIE-MEMBRAN
Title (fr)
PROTEINE G DU VIRUS RESPIRATOIRE SYNCYTIAL EXPRIMEE SUR MEMBRANE BACTERIENNE
Publication
Application
Priority
- FR 9501465 W 19951107
- FR 9413309 A 19941107
Abstract (en)
[origin: WO9614418A1] A method for preparing a peptide or protein, wherein (a) a DNA sequence coding for a heterologous polypeptide on a peptide sequence between amino acid residues 130 and 230 of respiratory syncytial virus protein G, sub-groups A and B, or a peptide sequence at least 80 % homologous thereto, and (b) means enabling the expression of the polypeptide on the bacterial membrane surface, are inserted into a bacterium which is not pathogenic for mammals. The resulting conjugate polypeptide and a live bacterium expressing same, pharmaceutical compositions containing them and their use for preparing a vaccine, as well as a DNA sequence coding for said polypeptide, are also disclosed.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 39/00 (2006.01); A61K 39/155 (2006.01); A61P 31/12 (2006.01); C07K 14/135 (2006.01); C07K 14/31 (2006.01); C12N 1/21 (2006.01); C12N 15/45 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01); C12R 1/44 (2006.01)
CPC (source: EP US)
A61P 31/12 (2018.01 - EP); C07K 14/005 (2013.01 - EP US); C07K 14/31 (2013.01 - EP US); A61K 38/00 (2013.01 - EP US); A61K 39/00 (2013.01 - EP US); C07K 2319/00 (2013.01 - EP US); C12N 2760/18522 (2013.01 - EP US); Y10S 435/882 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9614418 A1 19960517; AU 4120196 A 19960531; AU 704703 B2 19990429; CA 2204618 A1 19960517; EP 0789768 A1 19970820; FR 2726577 A1 19960510; FR 2726577 B1 19970131; JP H10509865 A 19980929; NZ 296563 A 19990429; US 6130091 A 20001010; ZA 959418 B 19960606
DOCDB simple family (application)
FR 9501465 W 19951107; AU 4120196 A 19951107; CA 2204618 A 19951107; EP 95939337 A 19951107; FR 9413309 A 19941107; JP 51510996 A 19951107; NZ 29656395 A 19951107; US 83650497 A 19970701; ZA 959418 A 19951107