EP 0791012 A1 19970827 - PEPTIDES EXHIBITING OXYTOCIN ANTAGONISTIC ACTIVITY

Title (en)

PEPTIDES EXHIBITING OXYTOCIN ANTAGONISTIC ACTIVITY

Title (de)

PEPTIDE MIT OXYTOCIN ANTAGONISTISCHER WIRKUNG

Title (fr)

PEPTIDES PRESENTANT UNE ACTIVITE ANTAGONISTE DE L'OXYTOCINE

Publication

EP 0791012 A1 19970827 (EN)

Application

EP 94921875 A 19940707

Priority

SE 9302414 A 19930713
SE 9400674 W 19940707

Abstract (en)

[origin: WO9502609A1] A peptide having formula (I) wherein Mpa is 3-mercaptopropionic acid residue (-S-CH2-CH2-CO-); X is D-tryptophan (D-Trp) or beta -(2-Naphtyl)-D-alanine (D-Nal); Ile is isoleucine; Y is alloisoleucine (alloIle) or (S)-2-Amino-3-ethyl-pentanoic acid (Ala( beta -Et2)); Asn is asparagine; alpha -Abu is alpha -aminobutyric acid residue (II) and N alpha MeOrn is N alpha -methyl-ornithine, is disclosed. The peptides may be used as an active ingredient in a medicament, especially in a pharmaceutical composition for therapeutic treatment of excessive uterus muscle contractions.

IPC 1-7

C07K 7/16; A61K 38/11

IPC 8 full level

A61K 38/00 (2006.01); A61P 13/02 (2006.01); A61P 15/00 (2006.01); C07K 7/16 (2006.01)

CPC (source: EP)

A61P 13/02 (2017.12); A61P 15/00 (2017.12); C07K 7/16 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9502609A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9502609 A1 19950126; AU 676071 B2 19970227; AU 7240694 A 19950213; CA 2163114 A1 19950126; CN 1126999 A 19960717; CZ 9896 A3 19960612; EP 0791012 A1 19970827; FI 960119 A0 19960110; FI 960119 A 19960110; HU 9503768 D0 19960228; HU T74874 A 19970228; IL 110267 A0 19941021; JP H09502427 A 19970311; KR 960702848 A 19960523; NO 955059 D0 19951213; NO 955059 L 19951213; PL 312568 A1 19960429; SE 501678 C2 19950410; SE 9302414 D0 19930713; SE 9302414 L 19950114; TW 268009 B 19960111; ZA 945090 B 19950222

DOCDB simple family (application)

SE 9400674 W 19940707; AU 7240694 A 19940707; CA 2163114 A 19940707; CN 94192763 A 19940707; CZ 9896 A 19940707; EP 94921875 A 19940707; FI 960119 A 19960110; HU 9503768 A 19940707; IL 11026794 A 19940711; JP 50449395 A 19940707; KR 19950705294 A 19951127; NO 955059 A 19951213; PL 31256894 A 19940707; SE 9302414 A 19930713; TW 83107195 A 19940805; ZA 945090 A 19940713