EP 0791059 A1 19970827 - PRODUCTION OF RECOMBINANT PEPTIDES AS NATURAL HYDROPHOBIC PEPTIDE ANALOGUES
Title (en)
PRODUCTION OF RECOMBINANT PEPTIDES AS NATURAL HYDROPHOBIC PEPTIDE ANALOGUES
Title (de)
HERSTELLUNG VON REKOMBINANTEN PEPTIDEN, ANALOGA VON HYDROPHOBEN NATÜRLICHEN PEPTIDEN
Title (fr)
PRODUCTION DE PEPTIDES RECOMBINANTS, ANALOGUES DE PEPTIDES NATURELS HYDROPHOBES
Publication
Application
Priority
- FR 9501464 W 19951107
- FR 9413307 A 19941107
Abstract (en)
[origin: WO9614409A1] A method for secreting a biologically active recombinant peptide as an analogue of a natural peptide having at least one hydrophobic region, by culturing cells transformed by a nucleic acid construct comprising elements for the expression and secretion of said peptide by the cell, and a sequence coding for a peptide with an amino acid sequence that differs from the natural peptide sequence in that it has at least one modification in a non-transmembrane hydrophobic region of the peptide; and by recovering the peptide and/or cells carrying said recombinant peptide. The resulting recombinant peptide, a corresponding DNA sequence, and a bacterium containing same, are also disclosed.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/12 (2006.01); A61K 35/74 (2006.01); A61K 35/76 (2006.01); A61K 36/06 (2006.01); A61K 38/00 (2006.01); A61K 39/265 (2006.01); A61K 48/00 (2006.01); A61P 11/00 (2006.01); C07K 14/135 (2006.01); C07K 14/435 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/52 (2006.01); C12P 21/00 (2006.01); A61K 39/00 (2006.01); C12R 1/19 (2006.01); C12R 1/44 (2006.01)
CPC (source: EP)
A61P 11/00 (2018.01); C07K 14/435 (2013.01); C12N 15/52 (2013.01); A61K 39/00 (2013.01); A61K 48/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9614409 A1 19960517; AU 4120096 A 19960531; AU 704594 B2 19990429; CA 2204511 A1 19960517; EP 0791059 A1 19970827; FR 2726576 A1 19960510; FR 2726576 B1 19970131; JP H10508479 A 19980825; NZ 296562 A 19991129; ZA 959417 B 19960611
DOCDB simple family (application)
FR 9501464 W 19951107; AU 4120096 A 19951107; CA 2204511 A 19951107; EP 95939336 A 19951107; FR 9413307 A 19941107; JP 51510895 A 19951107; NZ 29656295 A 19951107; ZA 959417 A 19951107