EP 0794789 A4 19990526 - INHIBITORS OF PRENYL TRANSFERASES
Title (en)
INHIBITORS OF PRENYL TRANSFERASES
Title (de)
PRENYLTRANSFERASE INHIBITOREN
Title (fr)
INHIBITEURS DES PRENYLE TRANSFERASES
Publication
Application
Priority
- US 9601559 W 19960111
- US 37168295 A 19950112
- US 45183995 A 19950530
- US 55255495 A 19951103
- US 58207696 A 19960102
Abstract (en)
[origin: WO9621456A1] Compounds which inhibit prenyl transferases, particularly farnysyltransferase and geranylgeranyl transferase I, processes for preparing the compounds, pharmaceutical compositions containing the compounds, and methods of use.
IPC 1-7
IPC 8 full level
C07D 277/20 (2006.01); A61K 31/195 (2006.01); A61K 31/215 (2006.01); A61K 31/42 (2006.01); A61K 31/421 (2006.01); A61K 31/425 (2006.01); A61K 31/426 (2006.01); A61K 31/44 (2006.01); A61K 38/00 (2006.01); A61K 38/55 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07C 323/25 (2006.01); C07C 323/59 (2006.01); C07C 323/60 (2006.01); C07C 329/06 (2006.01); C07D 207/34 (2006.01); C07D 213/56 (2006.01); C07D 215/38 (2006.01); C07D 217/22 (2006.01); C07D 257/04 (2006.01); C07D 263/48 (2006.01); C07D 277/38 (2006.01); C07D 277/40 (2006.01); C07D 307/66 (2006.01); C07K 5/103 (2006.01); C07K 5/107 (2006.01)
CPC (source: EP)
A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07C 323/25 (2013.01); C07C 323/59 (2013.01); C07C 323/60 (2013.01); C07D 207/34 (2013.01); C07D 215/38 (2013.01); C07D 217/22 (2013.01); C07D 263/48 (2013.01); C07D 277/38 (2013.01); C07D 307/66 (2013.01); C07K 5/1013 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [LX] US 5602098 A 19970211 - SEBTI SAID [US], et al
- [XP] VOGT, A. ET AL.: "A non-peptide Mimetic of Ras-CCAX : Selective Inhibition of Farnesytransferase and Ras Processing", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 2, 13 January 1995 (1995-01-13), pages 660 - 664, XP002084611
- [X] QIAN, Y. ET AL.: "Peptidomimetic inhibitors of p21RAS farnesyltransferase : hydrophobic functionalization leads to disruption of p21RAS membrane association in whole cells", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 4, no. 21, 1994, pages 2579 - 2584, XP002084612
- See references of WO 9621456A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9621456 A1 19960718; AU 4915796 A 19960731; CA 2207252 A1 19960718; CA 2207252 C 20140225; EP 0794789 A1 19970917; EP 0794789 A4 19990526; JP 2007016035 A 20070125; JP 3929069 B2 20070613; JP 4138826 B2 20080827; JP H10512266 A 19981124; MX 9705273 A 19980630
DOCDB simple family (application)
US 9601559 W 19960111; AU 4915796 A 19960111; CA 2207252 A 19960111; EP 96905380 A 19960111; JP 2006209503 A 20060801; JP 52188496 A 19960111; MX 9705273 A 19970711