EP 0796247 A1 19970924 - (-)-(3R)-3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL PHENOXY BUTYRIC ACID AS CELLULAR ADHESION INHIBITOR
Title (en)
(-)-(3R)-3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL PHENOXY BUTYRIC ACID AS CELLULAR ADHESION INHIBITOR
Title (de)
(-)-(3R)-3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL)PHENOXY)BUTYRIC ACID ALS ZELLADHÄSIONHEMMER
Title (fr)
ACIDE (-)-(3R)-3-METHYL-4-(4-(4-(4-PYRIDYL)PIPERAZIN-1-YL PHENOXY BUTYRIQUE INHIBITEUR D'ADHESION CELLULAIRE
Publication
Application
Priority
- GB 9601260 W 19960528
- GB 9518188 A 19950907
- US 45753895 A 19950601
Abstract (en)
[origin: WO9638416A1] The novel optically active compound (-)-(3R)-3-methyl-4-{4-[4-(4-pyridyl)-piperazin-1-yl]phenoxy}butyric acid, and pharmaceutically-acceptable salts, esters, amides or solvates thereof. Processes for the preparation of the compound, pharmaceutical compositions containing the compound and its use to inhibit cellular adhesion, for example platelet aggregation.
IPC 1-7
IPC 8 full level
A61K 31/495 (2006.01); A61P 7/02 (2006.01); C07C 69/675 (2006.01); C07C 309/73 (2006.01); C07D 213/74 (2006.01)
CPC (source: EP KR)
A61P 7/02 (2017.12 - EP); C07D 213/74 (2013.01 - EP KR)
Citation (search report)
See references of WO 9638416A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9638416 A1 19961205; AT 406675 B 20000725; AT A900596 A 19991215; AU 5827296 A 19961218; AU 710105 B2 19990916; BE 1009520 A5 19970401; BR 9606409 A 19970930; CA 2194397 A1 19961205; CH 691808 A5 20011031; CZ 26997 A3 19970813; DE 19680509 T1 19971204; DK 10697 A 19970401; EP 0796247 A1 19970924; ES 2137886 A1 19991216; ES 2137886 B1 20000816; FI 970393 A0 19970130; FI 970393 A 19970130; GB 2304340 A 19970319; GB 2304340 B 19980729; GB 9627127 D0 19970219; GR 1002702 B 19970522; HU 9700274 D0 19970428; HU P9700274 A2 19990628; HU P9700274 A3 20000228; IE 960405 A1 19961211; IL 118477 A0 19960912; IT 1290839 B1 19981214; IT MI961113 A0 19960531; IT MI961113 A1 19971201; JP 2885941 B2 19990426; JP H09512836 A 19971222; KR 100245957 B1 20000401; KR 970704689 A 19970906; LU 90008 B1 19970416; MC 2418 A1 19970523; MX 9700379 A 19970430; NL 1003243 C2 19961204; NO 307460 B1 20000410; NO 970437 D0 19970131; NO 970437 L 19970220; NZ 308597 A 19981125; PL 318440 A1 19970609; SE 510812 C2 19990628; SE 9700203 D0 19970124; SE 9700203 L 19970124; SK 13097 A3 19970806; TR 199700020 T1 19970422
DOCDB simple family (application)
GB 9601260 W 19960528; AT 900596 A 19960528; AU 5827296 A 19960528; BE 9600491 A 19960531; BR 9606409 A 19960528; CA 2194397 A 19960528; CH 22497 A 19960528; CZ 26997 A 19960528; DE 19680509 T 19960528; DK 10697 A 19970130; EP 96919906 A 19960528; ES 9750006 A 19960528; FI 970393 A 19970130; GB 9627127 A 19960528; GR 960100176 A 19960528; HU P9700274 A 19960528; IE 960405 A 19960531; IL 11847796 A 19960530; IT MI961113 A 19960531; JP 53628196 A 19960528; KR 19970700532 A 19970127; LU 90008 A 19970122; MC 2347 A 19960529; MX 9700379 A 19960528; NL 1003243 A 19960531; NO 970437 A 19970131; NZ 30859796 A 19960528; PL 31844096 A 19960528; SE 9700203 A 19970124; SK 13097 A 19960528; TR 9700020 T 19960528