Global Patent Index - EP 0796320 A4

EP 0796320 A4 19991124 - HUMAN DNA LIGASE III

Title (en)

HUMAN DNA LIGASE III

Title (de)

MENSCHLICHE DNA-LIGASE

Title (fr)

ADN-LIGASE III HUMAINE

Publication

EP 0796320 A4 19991124 (EN)

Application

EP 95902496 A 19941108

Priority

US 9412922 W 19941108

Abstract (en)

[origin: WO9614394A1] A human DNA Ligase III polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide via gene therapy for the treatment of disorders associated with a defect in DNA Ligase III. Antagonists against such polypeptides and their use as a therapeutic to destroy unwanted cells are also disclosed. Diagnostic assays to detect mutant DNA Ligase III genes are also disclosed.

IPC 1-7

C12N 1/21; C12N 5/10; C12N 9/00; C12N 15/52; C12N 15/63

IPC 8 full level

G01N 33/50 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); A61P 7/06 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07K 16/40 (2006.01); C12N 1/21 (2006.01); C12N 5/00 (2006.01); C12N 5/10 (2006.01); C12N 9/00 (2006.01); C12N 9/88 (2006.01); C12N 9/99 (2006.01); C12N 15/09 (2006.01); G01N 33/53 (2006.01); C12R 1/19 (2006.01); C12R 1/91 (2006.01)

CPC (source: EP)

A61P 7/06 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C12N 9/93 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

  • [X] AUFFRAY C. ET AL.: "The Genexpress cDNA program.", EMBL DATABASE ENTRY HSC0XA041; ACCESSION NUMBER Z42891, 6 November 1994 (1994-11-06), XP002114789
  • [T] WEI Y. F. ET AL.: "Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination.", MOLECULAR AND CELLULAR BIOLOGY, vol. 15, no. 6, June 1995 (1995-06-01), pages 3206 - 3216, XP002065032
  • See references of WO 9614394A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9614394 A1 19960517; AU 1174795 A 19960531; AU 687484 B2 19980226; EP 0796320 A1 19970924; EP 0796320 A4 19991124; JP H10508484 A 19980825

DOCDB simple family (application)

US 9412922 W 19941108; AU 1174795 A 19941108; EP 95902496 A 19941108; JP 51526796 A 19941108