EP 0796323 A1 19970924 - USE OF THE PROTEASE DOMAIN OF HUMAN PLASMINOGEN ACTIVATOR FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES
Title (en)
USE OF THE PROTEASE DOMAIN OF HUMAN PLASMINOGEN ACTIVATOR FOR THE TREATMENT OF THROMBOEMBOLIC DISEASES
Title (de)
VERWENDUNG DER PROTEASEDOMÄNE HUMANES GEWEBSPLASMINAKILIVATORS FÜR DIE BEHANDLUNG VON THROMBOEMBOLISCHEN ERKRANKUNGEN
Title (fr)
UTILISATION DU DOMAINE PROTEASE DE L'ACTIVATEUR PLASMINOGENE HUMAIN DANS LE TRAITEMENT DE MALADIES THROMBOEMBOLIQUES
Publication
Application
Priority
- DE 4443273 A 19941206
- EP 9504717 W 19951130
- US 45656695 A 19950601
Abstract (en)
[origin: WO9617928A1] The invention relates to the use of thromboembolic proteins. These contain, as their only structural portion effecting thrombolytic activity, the protease domain of human tissue type plasminogen activator. These derivatives show reduced side effects, such as a reduction in bleeding, while demonstrating remarkable in vivo efficacy. The effect is surprising, given their in vitro properties.
IPC 1-7
IPC 8 full level
C12N 9/72 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C12N 9/6459 (2013.01); C12Y 304/21069 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
See references of WO 9617928A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9617928 A1 19960613; AU 4259496 A 19960626; EP 0796323 A1 19970924
DOCDB simple family (application)
EP 9504717 W 19951130; AU 4259496 A 19951130; EP 95941060 A 19951130