Global Patent Index - EP 0797384 A4

EP 0797384 A4 2000-07-19 - ORGAN TRANSPLANT SOLUTIONS AND METHOD FOR TRANSPLANTING AN ORGAN

Title (en)

ORGAN TRANSPLANT SOLUTIONS AND METHOD FOR TRANSPLANTING AN ORGAN

Title (de)

LÖSUNGEN UND VERFAHREN FÜR DIE ORGANTRANSPLANTATION

Title (fr)

SOLUTIONS POUR LA TRANSPLANTATION D'ORGANES ET TECHNIQUE DE TRANSPLANTATION D'ORGANES

Publication

EP 0797384 A4 (EN)

Application

EP 95943059 A

Priority

  • US 9516065 W
  • US 35450394 A
  • US 56322295 A

Abstract (en)

[origin: WO9618293A1] There is provided cardioplegic solutions for arresting an organ intended for transplantation and preservation solutions for perfusing and storing an organ while awaiting transplantation. The cardioplegic solutions include, per liter of solution, a balanced isotonic solution of sodium, potassium, calcium, and magnesium ions and bicarbonate in a physiologically acceptable amount, at least 0.5 mu M of an amiloride-containing compound; and water sufficient to make a liter of solution. The preserving solutions include per liter of solution, a balanced isotonic solution of sodium, potassium, calcium, and magnesium ions and bicarbonate in physiologically acceptable amount, from about 1.0 mu M to about 5.0 mu M of an amiloride-containing compound; and water to make a liter of solution. In addition the preservation solution may contain other components such as EDTA, a small amount of adenosine, and at least one antioxidant. The amiloride-containing compound may be amiloride, hexamethylene amiloride, dimethyl amiloride, ethyl isopropyl amiloride or methyl isobutyl amiloride. There is also provided a method for arresting an organ, storing an organ and transplanting an organ all at room temperature for up to at least 24 hours.

IPC 1-7 (main, further and additional classification)

A01N 1/02

IPC 8 full level (invention and additional information)

A01N 1/02 (2006.01)

CPC (invention and additional information)

A01N 1/0226 (2013.01)

Citation (search report)

  • No further relevant documents disclosed
  • See also references of WO 9618293A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9618293 A1 19960620; AU 4420396 A 19960703; CA 2207324 A1 19960620; EP 0797384 A1 19971001; EP 0797384 A4 20000719; MX 9704374 A 19980228

INPADOC legal status


2002-01-02 [18D] APPLICATION DEEMED TO BE WITHDRAWN

- Effective date: 20010703

2000-07-19 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20000606

2000-07-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

1998-01-07 [RIN1] INVENTOR CHANGED BEFORE GRANT

- Inventor name: RAYMOND, RICHARD, M.

1997-10-01 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19970701

1997-10-01 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE