EP 0797384 A4 20000719 - ORGAN TRANSPLANT SOLUTIONS AND METHOD FOR TRANSPLANTING AN ORGAN
Title (en)
ORGAN TRANSPLANT SOLUTIONS AND METHOD FOR TRANSPLANTING AN ORGAN
Title (de)
LÖSUNGEN UND VERFAHREN FÜR DIE ORGANTRANSPLANTATION
Title (fr)
SOLUTIONS POUR LA TRANSPLANTATION D'ORGANES ET TECHNIQUE DE TRANSPLANTATION D'ORGANES
Publication
Application
Priority
- US 9516065 W 19951211
- US 35450394 A 19941212
- US 56322295 A 19951127
Abstract (en)
[origin: WO9618293A1] There is provided cardioplegic solutions for arresting an organ intended for transplantation and preservation solutions for perfusing and storing an organ while awaiting transplantation. The cardioplegic solutions include, per liter of solution, a balanced isotonic solution of sodium, potassium, calcium, and magnesium ions and bicarbonate in a physiologically acceptable amount, at least 0.5 mu M of an amiloride-containing compound; and water sufficient to make a liter of solution. The preserving solutions include per liter of solution, a balanced isotonic solution of sodium, potassium, calcium, and magnesium ions and bicarbonate in physiologically acceptable amount, from about 1.0 mu M to about 5.0 mu M of an amiloride-containing compound; and water to make a liter of solution. In addition the preservation solution may contain other components such as EDTA, a small amount of adenosine, and at least one antioxidant. The amiloride-containing compound may be amiloride, hexamethylene amiloride, dimethyl amiloride, ethyl isopropyl amiloride or methyl isobutyl amiloride. There is also provided a method for arresting an organ, storing an organ and transplanting an organ all at room temperature for up to at least 24 hours.
IPC 1-7
IPC 8 full level
A01N 1/02 (2006.01)
CPC (source: EP)
A01N 1/0226 (2013.01)
Citation (search report)
- No further relevant documents disclosed
- See references of WO 9618293A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9618293 A1 19960620; AU 4420396 A 19960703; CA 2207324 A1 19960620; EP 0797384 A1 19971001; EP 0797384 A4 20000719; MX 9704374 A 19980228
DOCDB simple family (application)
US 9516065 W 19951211; AU 4420396 A 19951211; CA 2207324 A 19951211; EP 95943059 A 19951211; MX 9704374 A 19951211