Global Patent Index - EP 0799305 A4

EP 0799305 A4 2000-01-26 - TRANSGENIC ANIMAL LACKING NATIVE AMYLOID PRECURSOR PROTEIN

Title (en)

TRANSGENIC ANIMAL LACKING NATIVE AMYLOID PRECURSOR PROTEIN

Title (de)

TRANSGENES TIER MIT MANGEL AN AMYLOIDEN VORLÄUFERPROTEIN

Title (fr)

ANIMAL TRANSGENIQUE PRESENTANT UNE CARENCE EN PROTEINE PRECURSEUR D'AMYLOIDE NATIVE

Publication

EP 0799305 A4 (EN)

Application

EP 95942534 A

Priority

  • US 9515672 W
  • US 34933494 A

Abstract (en)

[origin: WO9617926A1] The present invention relates to a transgenic nonhuman animal lacking native amyloid precursor protein. The transgenic mouse of the invention may be used in the study of Alzheimer's Disease and disorders involving the central nervous system.

IPC 1-7

C12N 5/00; C12N 15/00; C12N 15/63

IPC 8 full level

C12N 15/09 (2006.01); A01K 67/027 (2006.01); C07K 14/47 (2006.01); C12N 5/10 (2006.01); C12N 15/85 (2006.01)

CPC

A01K 67/0276 (2013.01); C12N 15/8509 (2013.01); C07K 14/4711 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0312 (2013.01); C12N 2517/02 (2013.01)

Citation (search report)

  • [X] WO 9314200 A1 19930722 - TSI CORP [US]
  • [X] MUCKE L. ET AL.: "Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice", BRAIN RESEARCH, vol. 666, no. 2, 1994, pages 151 - 167, XP002121613
  • [X] LANNFELT L. ET AL.: "Alzheimer's disease: molecular genetics and transgenic animal models", BEHAVIOURAL BRAIN RESEARCH, vol. 57, no. 2, 1993, pages 207 - 213, XP002121614
  • See also references of WO 9617926A1

DCS

AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE

DOCDB simple family

WO 9617926 A1 19960613; CA 2206789 A1 19960613; EP 0799305 A1 19971008; EP 0799305 A4 20000126; JP 2000504202 A 20000411