EP 0802897 A1 19971029 - NOVEL COMPOUNDS
Title (en)
NOVEL COMPOUNDS
Title (de)
VERBINDUNGEN
Title (fr)
COMPOSES NOUVEAUX
Publication
Application
Priority
- EP 9600158 W 19960108
- IT MI950033 A 19950110
- IT MI950032 A 19950110
- IT MI950031 A 19950110
Abstract (en)
[origin: WO9621638A1] A compound of formula (I), or a salt thereof, or a solvate thereof, wherein: R1 is an alkyl group or a substituted or unsubstituted phenyl group; R2 and R3 each independently represent hydrogen or alkyl; and either: RA represents T1 wherein T1 is hydrogen or alkyl; and RB represents a moiety of formula (a) wherein T2 and T3 each independently represents hydrogen, hydroxy, amino, alkoxy, alkylcarbonyloxy, optionally substituted phenoxy, optionally substituted benzyloxy, alkylamino, dialkylamino, chloro, alkyl, carboxy, carbalkoxy, carbamoyl, alkylcarbamoyl or T2 and T3 together represent a C3-5-alkylene chain each carbon atom of which is optionally substituted with up to three alkyl groups; or RA together with RB represents a moiety of formula (b), wherein R4, R5, R8 and R9 each independently represents hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, aralkyl or R4 and R5 together with the carbon atoms to which they are attached or R8 and R9 together with the carbon atomsto which they are attached form an optionally substituted phenylene ring; and R6 and R7 each independently represent hydrogen, alkyl, aryl, alkoxy; or R6 and R7 together with the carbon atom to which they are attached form a saturated heterocyclic ring; or RA represents a moiety of formula (c) and RB represents a moiety of formula (d), wherein T4, T5, T6 and T7 each independently represents hydrogen, alkoxy, alkylcabonyloxy, optionally substituted phenoxy, optionally substituted benzyloxy, alkylamino, dialkylamino, chloro, alkyl, carboxy, carbalkoxy, carbamoyl or alkylcarbamoyl; and X1 and Y each independently represents hydrogen or X1 together with Y represents a C3-5-alkylene chain, a moiety of formula -CO-NH-, -CH2-NH- or -CH2-O-; and X represents hydroxy, alkoxy or a group of formula NRsRt wherein Rs and Rt each independently represents hydrogen, alkyl, substituted alkyl, phenyl, substituted phenyl, phenylalkyl or heteroarylalkyl; or Rs and Rt together with the nitrogen atom to which they are attached represent a saturated heterocyclic group; a process for the preparation of such a compound, a pharmaceutical composition comprising such a compound and the use of such a compound in medicine.
IPC 1-7
C07C 69/734; A61K 31/215; A61K 31/16; A61K 31/19; C07C 59/64; C07C 233/11; C07C 233/18; C07C 205/56; C07D 313/12; C07D 267/18
IPC 8 full level
A61K 31/19 (2006.01); A61K 31/215 (2006.01); A61K 31/216 (2006.01); A61K 31/55 (2006.01); A61P 1/00 (2006.01); A61P 9/10 (2006.01); A61P 19/10 (2006.01); A61P 29/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07C 45/00 (2006.01); C07C 45/41 (2006.01); C07C 45/72 (2006.01); C07C 47/238 (2006.01); C07C 51/09 (2006.01); C07C 59/64 (2006.01); C07C 67/343 (2006.01); C07C 69/73 (2006.01); C07C 69/734 (2006.01); C07C 201/12 (2006.01); C07C 205/56 (2006.01); C07C 229/44 (2006.01); C07C 235/34 (2006.01); C07C 235/38 (2006.01); C07D 223/20 (2006.01); C07D 295/185 (2006.01); C07D 313/12 (2006.01)
CPC (source: EP)
A61K 31/00 (2013.01); A61K 31/216 (2013.01); A61K 31/55 (2013.01); A61P 1/00 (2017.12); A61P 9/10 (2017.12); A61P 19/10 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C07C 45/00 (2013.01); C07C 45/41 (2013.01); C07C 45/72 (2013.01); C07C 47/238 (2013.01); C07C 69/734 (2013.01); C07C 205/56 (2013.01); C07C 229/44 (2013.01); C07C 235/34 (2013.01); C07D 223/20 (2013.01); C07D 295/185 (2013.01); C07D 313/12 (2013.01)
Citation (search report)
See references of WO 9621638A1
Designated contracting state (EPC)
BE CH DE DK FR GB IT LI NL
DOCDB simple family (publication)
WO 9621638 A1 19960718; EP 0802897 A1 19971029; JP H10512553 A 19981202
DOCDB simple family (application)
EP 9600158 W 19960108; EP 96901276 A 19960108; JP 52145196 A 19960108