EP 0804076 A1 19971105 - GENE THERAPY INVOLVING CONCURRENT AND REPEATED ADMINISTRATION OF ADENOVIRUSES AND IMMUNOSUPPRESSIVE AGENTS
Title (en)
GENE THERAPY INVOLVING CONCURRENT AND REPEATED ADMINISTRATION OF ADENOVIRUSES AND IMMUNOSUPPRESSIVE AGENTS
Title (de)
GENTHERAPY DURCH GLEICHZEITIGE UND WIEDERHOLTE VERABREICHUNG VON ADENOVIRUS UND IMMUNSUPPRESIVEN MITTELN
Title (fr)
THERAPIE GENIQUE PAR ADMINISTRATION CONCURRENTE ET REPETEE D'ADENOVIRUS ET D'AGENTS IMMUNODEPRESSEURS
Publication
Application
Priority
- US 9513253 W 19951019
- US 32567994 A 19941019
- US 47848295 A 19950607
Abstract (en)
[origin: WO9612406A1] A method of effecting a gene therapy treatment in a host which comprises the steps of: (a) administering to a host concurrently (i) an adenoviral vector including at least one DNA sequence encoding a therapeutic agent and (ii) an immunosuppressive agent; (b) discontinuing the administration of said adenoviral vector and said immunosuppressive agent; and (c) repeating the administration of the adenoviral vector and the immunosuppressive agent at least once. The repeated course of treatment of administration of an adenoviral vector and an immunosuppressive agent provides for continued or increased expression of the at least one DNA sequence encoding the therapeutic agent.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/57 (2006.01); A61K 31/675 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 38/13 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 31/12 (2006.01); A61P 37/06 (2006.01); C12N 15/00 (2006.01); C12N 15/861 (2006.01); C12R 1/92 (2006.01)
CPC (source: EP)
A61K 31/70 (2013.01); A61K 38/13 (2013.01); A61K 48/00 (2013.01); A61P 31/12 (2017.12); A61P 37/06 (2017.12); C12N 15/86 (2013.01); C12N 2710/10343 (2013.01); C12N 2830/42 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9612406 A1 19960502; CA 2200869 A1 19960502; EP 0804076 A1 19971105; EP 0804076 A4 19981021; JP H10507758 A 19980728
DOCDB simple family (application)
US 9513253 W 19951019; CA 2200869 A 19951019; EP 95938753 A 19951019; JP 51401396 A 19951019