Title (en)

NSAID DELIVERY EMPLOYING A POWDERED HYDROCOLLOID GUM OBTAINABLE FROM HIGHER PLANTS

Title (de)

NSAID VERABREICHUNG UNTER VERWENDUNG EINES GEPULVERTEN AUS HÖHEREN PFLANZEN GEWINNBAREN HYDROKOLLOIDGUMMEN

Title (fr)

APPORT D'UN ANTI-INFLAMMATOIRE NON STEROIDIEN AU MOYEN D'UNE GOMME HYDROCOLLOIDALE EN POUDRE POUVANT ETRE OBTENUE A PARTIR DES PLANTES SUPERIEURES

Publication

EP 0804169 A1 19971105 (EN)

Application

EP 95944048 A 19951130

Priority

• US 9515599 W 19951130
• US 34760194 A 19941201

Abstract (en)

[origin: WO9616639A1] An oral-delivery pharmaceutical composition for reducing the gastric irritation effect of an NSAID in the upper GI tract of a mammal. The composition includes (a) a mucosal protective amount of a pharmaceutically-acceptable hydrocolloid gum obtainable from higher plants, (b) a dispersion-enhancing amount of another excipient and (c) a therapeutically-effective amount of an NSAID. Also disclosed is a process for preparing the composition and a method for reducing the gastric irritation effect of the NSAID by administering the composition. Also, disclosed is a composition particularly useful for preparing an aqueous suspension.

IPC 1-7

A61K 9/16

IPC 8 full level

A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/192 (2006.01); A61K 47/36 (2006.01)

CPC (source: EP)

A61K 9/205 (2013.01); A61K 31/192 (2013.01); A61K 31/616 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9616639 A1 19960606; AU 4595196 A 19960619; AU 690417 B2 19980423; CA 2205442 A1 19960606; CA 2205442 C 20030121; EP 0804169 A1 19971105; EP 0804169 A4 19980819; FI 972305 A0 19970530; FI 972305 A 19970530; JP H10509982 A 19980929; MX 9704079 A 19971231; NO 972485 D0 19970530; NO 972485 L 19970731

DOCDB simple family (application)

US 9515599 W 19951130; AU 4595196 A 19951130; CA 2205442 A 19951130; EP 95944048 A 19951130; FI 972305 A 19970530; JP 51907796 A 19951130; MX 9704079 A 19951130; NO 972485 A 19970530