EP 0804226 A1 19971105 - HUMAN CHOLINE ACETYLTRANSFERASE
Title (en)
HUMAN CHOLINE ACETYLTRANSFERASE
Title (de)
MENSCHLICHE CHOLIN ACETYLTRANSFERASE
Title (fr)
CHOLINE-ACETYLASE HUMAINE
Publication
Application
Priority
US 9413570 W 19941123
Abstract (en)
[origin: WO9615806A1] Human choline acetyltransferase polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of cognitive and neurological deficiencies or mental disturbances such as degenerative nervous system disorders, for example, Alzheimer's Disease, ALS and other cholinergic defects, and antagonists for treating Parkinson's Disease and other disorders relating to an over-expression of acetylcholine. Also disclosed are diagnostic methods for detecting a mutation in the human Choline Acetyltransferase nucleic acid sequence.
IPC 1-7
A61K 38/45; C12N 1/21; C12N 5/10; C12N 9/10; C12N 15/54; C12N 15/63
IPC 8 full level
A61K 38/45 (2006.01); A61K 48/00 (2006.01); A61P 25/00 (2006.01); A61P 25/02 (2006.01); A61P 25/28 (2006.01); C07K 16/40 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/10 (2006.01); C12N 15/00 (2006.01); C12N 15/02 (2006.01); C12N 15/09 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); A61K 38/00 (2006.01); C12R 1/19 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/28 (2017.12); C12N 9/1029 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
BE CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9615806 A1 19960530; AU 1260195 A 19960617; EP 0804226 A1 19971105; EP 0804226 A4 19991124; JP H10509871 A 19980929
DOCDB simple family (application)
US 9413570 W 19941123; AU 1260195 A 19941123; EP 95903602 A 19941123; JP 51679796 A 19941123