EP 0804235 A4 20010919 - ANTIBODIES TO P-SELECTIN AND THEIR USES
Title (en)
ANTIBODIES TO P-SELECTIN AND THEIR USES
Title (de)
ANTIKÖRPER GEGEN P-SELECTIN UND IHRE VERWENDUNGEN
Title (fr)
ANTICORPS DIRIGES CONTRE LA SELECTINE P ET LEURS UTILISATIONS
Publication
Application
Priority
- US 9404935 W 19940504
- US 9304274 W 19930504
- US 5729293 A 19930505
- US 20204794 A 19940225
Abstract (en)
[origin: WO9425067A1] The present invention relates to compositions and methods for treating inflammation and other pathological conditions using novel blocking P-selectin antibodies that inhibit adhesion of leukocytes to activated platelets and/or to activated vascular endothelium in vivo. Both murine and humanized antibodies are provided.
IPC 1-7
C07K 16/28; C07K 16/46; A61K 39/395; C07K 7/06; C07K 7/08; C12N 5/10; C12N 5/16; C12N 5/20; C12N 7/01; C12N 15/00; C12N 15/13; C12P 21/00; G01N 33/53
IPC 8 full level
C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12P 21/08 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/70564 (2013.01); C07K 16/2854 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01)
Citation (search report)
- [PX] WO 9321956 A1 19931111 - CYTEL CORP [US], et al
- [A] CARLOS T M ET AL: "Membrane proteins involved in phagocyte adherence to endothelium.", IMMUNOLOGICAL REVIEWS, (1990 APR) 114 5-28. REF: 122, XP001008136
- [A] SHARAR S R ET AL: "P - selectin blockade does not impair leukocyte host defense against bacterial peritonitis and soft tissue infection in rabbits.", JOURNAL OF IMMUNOLOGY, (1993 NOV 1) 151 (9) 4982-8., XP000999480
- See references of WO 9425067A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9425067 A1 19941110; EP 0804235 A1 19971105; EP 0804235 A4 20010919; FI 955261 A0 19951102; FI 955261 A 19960103
DOCDB simple family (application)
US 9404935 W 19940504; EP 94917301 A 19940504; FI 955261 A 19951102