Global Patent Index - EP 0804461 A1

EP 0804461 A1 19971105 - PROCESS FOR FOLDING OF PROTEINS LIKE RECOMBINANT HIRUDIN OR EPIDERMAL GROWTH FACTOR

Title (en)

PROCESS FOR FOLDING OF PROTEINS LIKE RECOMBINANT HIRUDIN OR EPIDERMAL GROWTH FACTOR

Title (de)

VERFAHREN ZUR FALTUNG VON PROTEINEN WIE REKOMBINANTEM HIRUDIN ODER EPIDEUMALEM WACHSTUMFAKTOR

Title (fr)

PROCEDE DE REPLIEMENT DE PROTEINES TELLES QUE L'HIRUDINE OU LE FACTEUR DE CROISSANCE EPIDERMIQUE DE RECOMBINAISON

Publication

EP 0804461 A1 19971105 (EN)

Application

EP 95926859 A 19950712

Priority

  • EP 95926859 A 19950712
  • EP 9502720 W 19950712
  • EP 94810437 A 19940725

Abstract (en)

[origin: WO9603425A1] The invention relates to a process for the preparation of a biologically active and correctly folded protein in the presence of a denaturing agent like urea or guanidine hydrochloride and the separation of the correctly folded protein therefrom directly. This process can be applied, for example, in the renaturation of recombinant proteins like hirudin or epidermal growth factor.

IPC 1-7

C07K 1/113; C07K 14/485; C07K 14/815

IPC 8 full level

C07K 1/113 (2006.01); C07K 14/485 (2006.01); C07K 14/815 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

C07K 1/1136 (2013.01); C07K 14/485 (2013.01); C07K 14/815 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9603425A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9603425 A1 19960208; AU 3109795 A 19960222; CA 2194177 A1 19960208; EP 0804461 A1 19971105; FI 970230 A0 19970120; FI 970230 A 19970120; IL 114699 A0 19951127; JP H11505507 A 19990521; NO 970081 D0 19970109; NO 970081 L 19970109; ZA 956137 B 19960307

DOCDB simple family (application)

EP 9502720 W 19950712; AU 3109795 A 19950712; CA 2194177 A 19950712; EP 95926859 A 19950712; FI 970230 A 19970120; IL 11469995 A 19950724; JP 50540295 A 19950712; NO 970081 A 19970109; ZA 956137 A 19950724