EP 0804546 A1 19971105 - HUMAN PROSTATIC SPECIFIC REDUCTASE
Title (en)
HUMAN PROSTATIC SPECIFIC REDUCTASE
Title (de)
MENSCHLICHE, PROSTATA-SPEZIFISCHE REDUKTASE
Title (fr)
REDUCTASE SPECIFIQUE DE LA PROSTATE CHEZ L'HOMME
Publication
Application
Priority
US 9501827 W 19950120
Abstract (en)
[origin: WO9622360A1] A human prostatic specific reductase polypeptide and polynucleotides encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides as a diagnostic marker for prostate cancer and as an agent to determine if the prostate cancer has metastasized. Also disclosed are antibodies specific to the prostatic specific reductase polypeptide which may be used to target prostate cancer cells and be used as part of a prostate cancer vaccine. Methods of screening for agonists and antagonists for the polypeptide and therapeutic uses of the antagonists are also dislcosed.
IPC 1-7
C12N 1/21; C12N 5/10; C12N 9/02; C12N 15/10; C12N 15/11; C12N 15/12; C12N 15/53; C12N 15/63; C07K 14/47; C12Q 1/68; C12Q 1/26
IPC 8 full level
G01N 33/50 (2006.01); C07K 16/40 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 9/02 (2006.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); C12R 1/19 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP US)
C12N 9/0004 (2013.01 - EP); A61K 38/00 (2013.01 - EP); A61K 39/00 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9622360 A1 19960725; AU 1918095 A 19960807; EP 0804546 A1 19971105; EP 0804546 A4 20000920; JP H10513044 A 19981215
DOCDB simple family (application)
US 9501827 W 19950120; AU 1918095 A 19950120; EP 95911712 A 19950120; JP 52222496 A 19950120