EP 0804568 A2 19971105 - MULTIMERIC FORMS OF MEMBERS OF THE STEROID/THYROID SUPERFAMILY OF RECEPTORS WITH THE ULTRASPIRACLE RECEPTOR
Title (en)
MULTIMERIC FORMS OF MEMBERS OF THE STEROID/THYROID SUPERFAMILY OF RECEPTORS WITH THE ULTRASPIRACLE RECEPTOR
Title (de)
MULTIMERE FORMEN AUS MITGLIEDERN DER STERIOD/THYROID-REZEPTORSUPERFAMILIE UND DER ULTRASPIRALISIERTEN REZEPTOREN
Title (fr)
FORMES MULTIMERES D'ELEMENTS DE LA SUPERFAMILLE STEROIDE/THYROIDE DE RECEPTEURS REUNIS AU RECEPTEUR D'ULTRASPIRACLE
Publication
Application
Priority
- US 9306296 W 19930701
- US 90790892 A 19920702
Abstract (en)
[origin: WO9401558A2] In accordance with the present invention, it has been discovered that various members of the steroid/thyroid superfamily of receptors can interact with the insect-derived ultraspiracle receptor, to form multimeric species. Accordingly, the interaction of at least one member of the steroid/thyroid superfamily of receptors with at least the dimerization domain of the ultraspiracle receptor modulates the ability of said member of the steroid/thyroid superfamily of receptors to transactivate transcription of genes maintained under hormone expression control in the presence of the cognate ligand for said member of the superfamily.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); C07K 14/44 (2006.01); C07K 14/72 (2006.01); C07K 19/00 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
C07K 14/44 (2013.01); C07K 14/721 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01)
Citation (search report)
See references of WO 9401558A2
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9401558 A2 19940120; WO 9401558 A3 19940526; AU 4769793 A 19940131; CA 2137462 A1 19940120; EP 0804568 A2 19971105; JP H08501211 A 19960213
DOCDB simple family (application)
US 9306296 W 19930701; AU 4769793 A 19930701; CA 2137462 A 19930701; EP 94904904 A 19930701; JP 50343194 A 19930701