EP 0808171 A2 19971126 - COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITOR, SIDE-EFFECT-REDUCED AMOUNT OF ALDOSTERONE ANTAGONIST AND DIURETIC
Title (en)
COMBINATION OF ANGIOTENSIN CONVERTING ENZYME INHIBITOR, SIDE-EFFECT-REDUCED AMOUNT OF ALDOSTERONE ANTAGONIST AND DIURETIC
Title (de)
KOMBINATION VON ANGIOTENSIN-CONVERTING-ENZYME HEMMERN MIT NEBENWIRKUNGREDUZIERENDE, VERRINGERTE MENGE VON ALDOSTERONANTAGONIST UND DIURETIKUM
Title (fr)
ASSOCIATION COMPRENANT UN INHIBITEUR DE L'ENZYME DE CONVERSION DE L'ANGIOTENSINE, UNE DOSE A EFFETS SECONDAIRES REDUITS D'UN ANTAGONISTE D'ALDOSTERONE, ET UN DIURETIQUE
Publication
Application
Priority
- US 9601764 W 19960209
- US 38685895 A 19950210
Abstract (en)
[origin: WO9624372A2] Combinations of an ACE inhibitor, an aldosterone receptor antagonist and a diuretic, i.e., "triple therapy" combinations, are described for use in treatment of circulatory disorders. Of particular interest are triple therapies using captopril or enalapril co-administered with a low-dose of spironolactone and furosemide. This triple therapy would be particularly useful to treat or prevent the progression of congestive heart failure while avoiding or reducing aldosterone-antagonist-induced side effects such as hyperkalemia.
IPC 1-7
IPC 8 full level
C07D 307/94 (2006.01); A61K 31/365 (2006.01); A61K 31/585 (2006.01); A61K 38/55 (2006.01); A61K 45/06 (2006.01); A61P 7/00 (2006.01); A61P 7/10 (2006.01); A61P 9/00 (2006.01); A61P 9/12 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP KR)
A61K 31/401 (2013.01 - EP); A61K 31/585 (2013.01 - EP); A61K 38/55 (2013.01 - KR); A61K 45/06 (2013.01 - EP); A61P 7/00 (2017.12 - EP); A61P 7/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 43/00 (2017.12 - EP)
Citation (search report)
See references of WO 9624372A2
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9624372 A2 19960815; WO 9624372 A3 19960926; AU 4866196 A 19960827; BR 9607612 A 19980609; CA 2212712 A1 19960815; EP 0808171 A2 19971126; EP 1201248 A2 20020502; EP 1201248 A3 20020508; JP H10513472 A 19981222; KR 19980702100 A 19980715; NZ 302578 A 20010525; NZ 510572 A 20021126
DOCDB simple family (application)
US 9601764 W 19960209; AU 4866196 A 19960209; BR 9607612 A 19960209; CA 2212712 A 19960209; EP 01128866 A 19960209; EP 96904600 A 19960209; JP 52444296 A 19960209; KR 19970705495 A 19970809; NZ 30257896 A 19960209; NZ 51057296 A 19960209