EP 0811059 A4 19980401 - HUMAN CHEMOKINE BETA-11 AND HUMAN CHEMOKINE ALPHA-1
Title (en)
HUMAN CHEMOKINE BETA-11 AND HUMAN CHEMOKINE ALPHA-1
Title (de)
MENSCHLICHE CHEMOKINE BETA-11 UND ALPHA-1
Title (fr)
CHEMOKINE HUMAINE BETA-11 ET CHEMOKINE HUMAINE ALPHA-1
Publication
Application
Priority
US 9501780 W 19950208
Abstract (en)
[origin: WO9624668A1] Human chemokine polypeptides and DNA (RNA) encoding such chemokine polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemokine polypeptides for the treatment of leukemia, tumors, chronic infections, auto-immune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemokine polypeptides and their use as a therapeutic to treat rheumatoid arthritis, auto-immune and chronic and acute inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the the polynucleotides encoding the chemokine polypeptides and for detecting altered levels of the polypeptide in a host.
IPC 1-7
C12N 15/00; C12N 1/20; C07K 14/52; C07K 16/24; C12Q 1/68; A61K 38/19
IPC 8 full level
C12N 15/09 (2006.01); A61K 35/76 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 48/00 (2006.01); A61P 33/00 (2006.01); A61P 37/00 (2006.01); A61P 43/00 (2006.01); C07K 14/52 (2006.01); C07K 16/24 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01); C12R 1/19 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP)
A61P 33/00 (2017.12); A61P 37/00 (2017.12); A61P 43/00 (2017.12); C07K 14/521 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [E] WO 9622374 A1 19960725 - INCYTE PHARMA INC [US], et al
- [E] WO 9617868 A1 19960613 - INCYTE PHARMA INC [US], et al
- See references of WO 9624668A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9624668 A1 19960815; AU 1916795 A 19960827; EP 0811059 A1 19971210; EP 0811059 A4 19980401; JP H10513355 A 19981222
DOCDB simple family (application)
US 9501780 W 19950208; AU 1916795 A 19950208; EP 95911695 A 19950208; JP 52423096 A 19950208