EP 0812354 A2 19971217 - HUMAN RETINOID X RECEPTOR - GAMMA (hRXR-GAMMA)
Title (en)
HUMAN RETINOID X RECEPTOR - GAMMA (hRXR-GAMMA)
Title (de)
MENSCHLICHER RETINOID X-GAMMA REZEPTOR (hRXR-GAMMA)
Title (fr)
RECEPTEUR -g(g) DE RETINOIDE X HUMAIN (hRXR-GAMMA)
Publication
Application
Priority
- US 9600847 W 19960119
- US 37742395 A 19950123
Abstract (en)
[origin: WO9623070A2] The present invention relates to a novel retinoid receptor, human retinoid X receptor gamma . hRXR gamma modulates transcription of certain genes in the presence of certain retinoid compounds. hRXR gamma differs from known retinoid receptors in nucleotide sequence, amino acid sequence, and expression pattern in tissues. The invention provides isolated, purified, or enriched nucleic acid encoding hRXR gamma polypeptides and vectors containing thereof, cells transformed with such vectors, and methods of screening for compounds capable of binding hRXR gamma polypeptides. The invention also provides isolated, purified, enriched, or recombinant hRXR gamma polypeptides, antibodies having specific binding affinity to hRXR gamma polypeptides, and hybridomas producing such antibodies.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C12N 15/12 (2006.01)
CPC (source: EP)
C07K 14/70567 (2013.01)
Citation (search report)
See references of WO 9623070A2
Designated contracting state (EPC)
CH DE FR GB IT LI NL
DOCDB simple family (publication)
WO 9623070 A2 19960801; WO 9623070 A3 19960926; AU 4763796 A 19960814; CA 2211142 A1 19960801; EP 0812354 A2 19971217
DOCDB simple family (application)
US 9600847 W 19960119; AU 4763796 A 19960119; CA 2211142 A 19960119; EP 96903616 A 19960119