EP 0815220 A4 20001011 - HUMAN AMINE TRANSPORTER
Title (en)
HUMAN AMINE TRANSPORTER
Title (de)
MENSCHLICHER AMINTRANSPORTER
Title (fr)
TRANSPORTEUR D'AMINE HUMAINE
Publication
Application
Priority
US 9502645 W 19950301
Abstract (en)
[origin: WO9627009A1] A Human amine transporter polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also provided are methods for detecting agonists and antagonists to such polypeptide and the use of agonists and antagonists for treating diseases related to the under-expression and over-expression of the Human amine transporter of the present invention. Also disclosed are methods for detecting mutations in the nucleic acid sequence encoding the polypeptide and for detecting altered levels of the soluble form of the polypeptide.
IPC 1-7
IPC 8 full level
G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 25/00 (2006.01); A61P 25/20 (2006.01); A61P 25/24 (2006.01); A61P 25/26 (2006.01); A61P 43/00 (2006.01); C07K 14/47 (2006.01); C07K 16/18 (2006.01); C12N 1/21 (2006.01); C12N 15/09 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); C12P 21/08 (2006.01); C12Q 1/02 (2006.01); C12Q 1/68 (2006.01); C12R 1/19 (2006.01)
CPC (source: EP)
A61P 25/00 (2017.12); A61P 25/20 (2017.12); A61P 25/24 (2017.12); A61P 25/26 (2017.12); A61P 43/00 (2017.12); C07K 14/47 (2013.01); A61K 38/00 (2013.01)
Citation (search report)
- [X] WO 9325699 A1 19931223 - UNIV CALIFORNIA [US]
- [X] WO 9416718 A1 19940804 - NEUROSPHERES LTD [CA], et al
- [X] ERICKSON JEFFREY D ET AL: "Functional identification and molecular cloning of a human brain vesicle monoamine transporter.", JOURNAL OF NEUROCHEMISTRY, vol. 61, no. 6, 1993, pages 2314 - 2317, XP000916925, ISSN: 0022-3042
- [X] WEIHE EBERHARD ET AL: "Localization of vesicular monoamine transporter isoforms (VMAT1 and VMAT2) to endocrine cells and neurons in rat.", JOURNAL OF MOLECULAR NEUROSCIENCE, vol. 5, no. 3, 1994, pages 149 - 164, XP000916930, ISSN: 0895-8696
- [T] ERICKSON JEFFREY D ET AL: "Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 1996, vol. 93, no. 10, 1996, pages 5166 - 5171, XP002143793, ISSN: 0027-8424
- See references of WO 9627009A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9627009 A1 19960906; AU 2271995 A 19960918; EP 0815220 A1 19980107; EP 0815220 A4 20001011; JP H11506309 A 19990608
DOCDB simple family (application)
US 9502645 W 19950301; AU 2271995 A 19950301; EP 95916097 A 19950301; JP 52621096 A 19950301