Global Patent Index - EP 0819127 A1

EP 0819127 A1 19980121 - IMIDAZO ¬1,2-a PYRIDINE DERIVATIVES

Title (en)

IMIDAZO ¬1,2-a PYRIDINE DERIVATIVES

Title (de)

IMIDAZO¬1,2-a PYRIDINDERIVATE

Title (fr)

DERIVES DE PYRIDINE IMIDAZO ¬1,2-a

Publication

EP 0819127 A1 19980121 (EN)

Application

EP 96909164 A 19960402

Priority

  • EP 9601438 W 19960402
  • GB 9506965 A 19950404
  • GB 9512099 A 19950614
  • GB 9516117 A 19950805

Abstract (en)

[origin: WO9631509A1] The invention provides the compounds of formula (I) and pharmaceutically acceptable derivatives thereof in which: R<0> represents halogen; R<1> and R<2> are independently selected from H, halogen, C1-4alkyl, C1-4alkyl substituted by one or more fluorine atoms, C1-4alkoxy, C1-4hydroxyalkyl, SC1-4alkyl, C(O)H or C(O)C1-4alkyl; and R<3> represents C1-4alkyl. Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of the pain, fever, inflammation of a variety of conditions and diseases.

IPC 1-7

C07D 471/04; A61K 31/435

IPC 8 full level

A61K 31/435 (2006.01); A61P 29/00 (2006.01); C07D 471/04 (2006.01)

CPC (source: EP KR)

A61P 29/00 (2018.01 - EP); C07D 471/04 (2013.01 - EP KR)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9631509 A1 19961010; AU 5276696 A 19961023; BG 101934 A 19990430; CA 2216809 A1 19961010; CN 1186492 A 19980701; CZ 313397 A3 19980318; EA 199700209 A1 19980430; EP 0819127 A1 19980121; HU P9801602 A2 19981130; HU P9801602 A3 19990128; IS 4570 A 19970925; JP H11501049 A 19990126; KR 19980703559 A 19981105; MX 9707379 A 19971129; NO 974595 D0 19971003; NO 974595 L 19971203; NZ 304886 A 19981125; PL 322623 A1 19980202; SK 133297 A3 19980708; TR 199701105 T1 19980221

DOCDB simple family (application)

EP 9601438 W 19960402; AU 5276696 A 19960402; BG 10193497 A 19970930; CA 2216809 A 19960402; CN 96194403 A 19960402; CZ 313397 A 19960402; EA 199700209 A 19960402; EP 96909164 A 19960402; HU P9801602 A 19960402; IS 4570 A 19970925; JP 52997196 A 19960402; KR 19970706963 A 19971002; MX 9707379 A 19960402; NO 974595 A 19971003; NZ 30488696 A 19960402; PL 32262396 A 19960402; SK 133297 A 19960402; TR 9701105 T 19960402