Title (en)

THROMBIN INHIBITORS

Title (de)

THROMBIN-INHIBITOREN

Title (fr)

INHIBITEURS DE THROMBINE

Publication

EP 0820453 A4 20010829 (EN)

Application

EP 96911520 A 19960401

Priority

• US 9604460 W 19960401
• US 41624495 A 19950404

Abstract (en)

[origin: WO9631504A1] A compound which inhibits human thrombin and has the structure (I) such as (II).

IPC 1-7

C07D 401/12; C07D 277/04; C07D 205/04; C07D 207/04; C07D 279/00; C07D 221/06; C07D 285/16; C07D 231/04; A61K 31/44; A61K 31/445; C07K 5/06

IPC 8 full level

A61K 38/55 (2006.01); A61P 7/02 (2006.01); A61P 43/00 (2006.01); C07K 5/02 (2006.01); C07K 5/06 (2006.01); C07K 5/065 (2006.01); C07K 5/078 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61P 7/02 (2017.12); A61P 43/00 (2017.12); C07K 5/0222 (2013.01); C07K 5/06078 (2013.01); C07K 5/06139 (2013.01); C07K 5/06191 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

• [A] WO 9425051 A1 19941110 - MERCK & CO INC [US], et al
• [X] PATENT ABSTRACTS OF JAPAN vol. 011, no. 332 (C - 455) 29 October 1987 (1987-10-29)
• [A] KIKUMOTO R ET AL: "SELECTIVE INHIBITION OF THROMBIN BY (2R,4R)-4-METHYL-1-U(38METHYL-1,2,3,4-TETRAHYDRO-8-QUINOLINYL) SULFONYL-L-ARGINYL)-2-PIPERIDINECARBOX YLIC ACID", BIOCHEMISTRY,US,AMERICAN CHEMICAL SOCIETY. EASTON, PA, vol. 23, no. 1, 3 January 1984 (1984-01-03), pages 85 - 90, XP002049060, ISSN: 0006-2960
• See references of WO 9631504A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9631504 A1 19961010; AU 5438596 A 19961023; AU 698911 B2 19981112; CA 2216859 A1 19961010; EP 0820453 A1 19980128; EP 0820453 A4 20010829; JP H11503161 A 19990323

DOCDB simple family (application)

US 9604460 W 19960401; AU 5438596 A 19960401; CA 2216859 A 19960401; EP 96911520 A 19960401; JP 53040896 A 19960401