EP 0823941 A1 19980218 - HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENOMICE
Title (en)
HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENOMICE
Title (de)
MENSCHLICHE ANTIKÖRPER AUS XENOMÄUSEN
Title (fr)
ANTICORPS HUMAINS DERIVES DE XENO-SOURIS IMMUNISEES
Publication
Application
Priority
- CA 2219486 A 19950428
- US 9505500 W 19950428
Abstract (en)
[origin: WO9634096A1] Antibodies with fully human variable regions against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.
IPC 1-7
IPC 8 full level
C07K 16/00 (2006.01); C07K 16/12 (2006.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); C07K 16/42 (2006.01); C12N 15/00 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 16/00 (2013.01); C07K 16/1282 (2013.01); C07K 16/241 (2013.01); C07K 16/244 (2013.01); C07K 16/2812 (2013.01); C07K 16/2854 (2013.01); C07K 16/2875 (2013.01); C07K 16/4291 (2013.01); A61K 38/00 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9634096 A1 19961031; AU 2466895 A 19961118; CA 2219486 A1 19961031; EP 0823941 A1 19980218; EP 0823941 A4 20010919
DOCDB simple family (application)
US 9505500 W 19950428; AU 2466895 A 19950428; CA 2219486 A 19950428; EP 95918935 A 19950428