Title (en)

HERPES SIMPLEX TYPE 1 PROTEASE MUTANTS AND VECTORS

Title (de)

HERPES SIMPLEX TYP I PROTEASEMUTANTEN UND VEKTOREN

Title (fr)

MUTANTS DE LA PROTEASE DU VIRUS DE L'HERPES SIMPLEX DU TYPE 1 ET VECTEURS ASSOCIES

Publication

EP 0828823 A4 19990210 (EN)

Application

EP 96916676 A 19960528

Priority

• US 9607795 W 19960528
• US 45755895 A 19950601

Abstract (en)

[origin: WO9638546A1] Herpes Simplex Type 1 viruses having mutated protease genes are described, also are methods for introducing a point mutation in the protease gene, vectors used in this process, and host cells transformed with these vectors.

IPC 1-7

C12N 7/01; C12N 15/00; C12N 15/38; C12N 1/21; C12N 5/10

IPC 8 full level

C12N 7/00 (2006.01); C12N 7/01 (2006.01); C12N 9/50 (2006.01); C12N 15/869 (2006.01)

CPC (source: EP)

C12N 7/00 (2013.01); C12N 9/503 (2013.01); C12N 15/86 (2013.01); C12N 2710/16643 (2013.01)

Citation (search report)

• [X] EP 0514830 A2 19921125 - ARCH DEV CORP [US]
• [A] EP 0176170 A1 19860402 - MERIEUX INST [FR]
• [PX] REGISTER R.B. & SHAFER J.A.: "A facile system for construction of HSV-1 variants: site directed mutation of the UL26 protease gene in HSV-1", J. VIROL. METHODS, vol. 57, no. 2, 5 April 1996 (1996-04-05), pages 181 - 193, XP002086857
• See references of WO 9638546A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9638546 A1 19961205; CA 2222877 A1 19961205; EP 0828823 A1 19980318; EP 0828823 A4 19990210

DOCDB simple family (application)

US 9607795 W 19960528; CA 2222877 A 19960528; EP 96916676 A 19960528