EP 0830375 A1 19980325 - HUMAN INHIBITOR OF APOPTOSIS GENE 1
Title (en)
HUMAN INHIBITOR OF APOPTOSIS GENE 1
Title (de)
MENSCHLICHER INHIBITOR DES APOPTOSEGENS 1
Title (fr)
INHIBITEUR HUMAIN DU GENE 1 DE L'APOPTOSE
Publication
Application
Priority
- CA 2220670 A 19950511
- US 9505922 W 19950511
Abstract (en)
[origin: WO9635703A1] A human inhibitor of apoptosis polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for the treatment of degenerative diseases, rheumatoid arthritis, septic shock, as an antiviral defense mechanism and to prevent the death of cells during trauma and strokes. Antagonists against such polypeptides and their use as a therapeutic to promote cell development, kill viral infections, promote tissue differentiation and development and maintain tissue homeostasis are also disclosed (tumors). Diagnostic methods for detecting mutations in the nucleic acid sequence encoding hIAP-1 protein are also disclosed.
IPC 1-7
IPC 8 full level
C07K 14/47 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C07K 14/4747 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C12N 2799/026 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9635703 A1 19961114; AU 2548095 A 19961129; CA 2220670 A1 19961114; EP 0830375 A1 19980325; EP 0830375 A4 20011121
DOCDB simple family (application)
US 9505922 W 19950511; AU 2548095 A 19950511; CA 2220670 A 19950511; EP 95919804 A 19950511