Global Patent Index - EP 0831854 A1

EP 0831854 A1 19980401 - OLIGONUCLEOTIDES HAVING PHOSPHOROTHIOATE LINKAGES OF HIGH CHIRAL PURITY

Title (en)

OLIGONUCLEOTIDES HAVING PHOSPHOROTHIOATE LINKAGES OF HIGH CHIRAL PURITY

Title (de)

OLIGONUKLEOTIDE MIT PHOSPHOROTHIOAT-BINDUNGEN VON HOHER CHIRALER REINHEIT

Title (fr)

OLIGONUCLEOTIDES DE GRANDE PURETE CHIRALE AYANT DES LIAISONS PHOSPHOROTHIOATE

Publication

EP 0831854 A1 19980401 (EN)

Application

EP 96921270 A 19960605

Priority

  • US 9608757 W 19960605
  • US 47196795 A 19950606
  • US 46759795 A 19950606
  • US 46844795 A 19950606
  • US 46856995 A 19950606
  • US 46669295 A 19950606
  • US 47196695 A 19950606
  • US 46985195 A 19950606
  • US 47012995 A 19950606

Abstract (en)

[origin: WO9639154A1] Sequence-specific phosphorothioate oligonucleotides comprising nucleoside units which are joined together by either substantially all Sp or substantially all Rp phosphorothioate intersugar linkages are provided. Such sequence-specific phosphorothioate oligonucleotides having substantially chirally pure intersugar linkages are prepared by enzymatic or chemical synthesis.

IPC 1-7

A61K 31/70; C07H 21/00

IPC 8 full level

C12N 15/09 (2006.01); A61K 31/70 (2006.01); A61K 31/7088 (2006.01); A61K 31/7125 (2006.01); A61K 48/00 (2006.01); A61P 1/16 (2006.01); A61P 25/00 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 31/12 (2006.01); A61P 31/14 (2006.01); A61P 31/18 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07H 21/00 (2006.01); C07H 21/04 (2006.01); C12N 15/113 (2010.01)

CPC (source: EP)

A61P 1/16 (2017.12); A61P 25/00 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 31/14 (2017.12); A61P 31/18 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C12N 15/1131 (2013.01); C12N 15/1132 (2013.01); C12N 15/1133 (2013.01); C12N 15/1135 (2013.01); C12N 15/1137 (2013.01); C12N 15/1138 (2013.01); C12N 2310/315 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9639154 A1 19961212; AU 6252896 A 19961224; AU 698739 B2 19981105; CA 2223103 A1 19961212; EP 0831854 A1 19980401; EP 0831854 A4 20010124; JP 2001103987 A 20010417; JP 2001114798 A 20010424; JP H10510433 A 19981013; NO 975558 D0 19971202; NO 975558 L 19980126

DOCDB simple family (application)

US 9608757 W 19960605; AU 6252896 A 19960605; CA 2223103 A 19960605; EP 96921270 A 19960605; JP 2000262865 A 20000831; JP 2000262871 A 20000831; JP 50125497 A 19960605; NO 975558 A 19971202