EP 0832216 A1 19980401 - FIBROBLAST GROWTH FACTOR 15
Title (en)
FIBROBLAST GROWTH FACTOR 15
Title (de)
FIBROBLASTER WACHSTUMSFAKTOR
Title (fr)
FACTEUR 15 DE CROISSANCE DES FIBROBLASTES
Publication
Application
Priority
US 9507156 W 19950605
Abstract (en)
[origin: WO9639509A1] Disclosed is a human Fibroblast growth factor 15 polypeptide and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for stimulating revascularization, for treating wounds and prevent neuronal damage. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the coding sequence and alterations in the concentration of the polypeptides in a sample derived from a host are also disclosed.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/22 (2006.01); A61K 39/395 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 7/02 (2006.01); A61P 9/08 (2006.01); A61P 9/10 (2006.01); A61P 25/00 (2006.01); A61P 25/28 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/50 (2006.01); C07K 16/22 (2006.01); C12N 5/10 (2006.01); C12N 15/00 (2006.01); C12N 15/12 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01); C12R 1/91 (2006.01)
CPC (source: EP KR)
A61P 7/02 (2017.12 - EP); A61P 9/08 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07K 14/50 (2013.01 - EP KR); C12N 15/11 (2013.01 - KR); A61K 38/00 (2013.01 - EP); C12N 2799/026 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9639509 A1 19961212; AU 2767495 A 19961224; AU 711647 B2 19991021; CA 2217301 A1 19961212; EP 0832216 A1 19980401; EP 0832216 A4 19990616; JP H11506919 A 19990622; KR 19990008319 A 19990125
DOCDB simple family (application)
US 9507156 W 19950605; AU 2767495 A 19950605; CA 2217301 A 19950605; EP 95922978 A 19950605; JP 50036496 A 19950605; KR 19970707845 A 19971105