EP 0832238 A1 19980401 - STREPTOCOCCAL HEAT SHOCK PROTEINS MEMBERS OF THE HSP70 FAMILY
Title (en)
STREPTOCOCCAL HEAT SHOCK PROTEINS MEMBERS OF THE HSP70 FAMILY
Title (de)
STREPTOKOKKEN-HITZESCHOCK-PROTEINE, MITGLIEDER DER HSP70-FAMILIE
Title (fr)
PROTEINES STREPTOCOCCIQUES DE CHOC THERMIQUE MEMBRES DE LA FAMILLE 70 DES PROTEINES DE CHOC THERMIQUE
Publication
Application
Priority
- CA 9600322 W 19960517
- US 47253495 A 19950607
- US 180595 P 19950804
Abstract (en)
[origin: WO9640928A1] Novel heat shock proteins (HSPs) of Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus agalactiae having apparent molecular masses of 70-72 kDa, immunologically related polypeptides, the nucleotide and derived amino acid sequences of HSP72 of S. pneumoniae (SEQ ID NO:4; SEQ ID NO:5), the nucleotide and derived amino acid sequences of HSP70 of S. pyogenes (SEQ ID NO:19; SEQ ID NO:20), the nucleotide and derived amino acid sequences of HSP 70 of S. agalactiae (SEQ ID NO:21; SEQ ID NO:22), antibodies that bind to the HSPs, and recombinant DNA methods for the production of the HSPs and immunologically related polypeptides are described. The polypeptides, DNA sequences and antibodies of this invention provide new means for the diagnosis, prevention and/or treatment of Streptococcal disease.
IPC 1-7
C12N 15/31; C07K 14/315; C12N 1/21; C07K 16/12; A61K 39/09; A61K 39/395; G01N 33/569; C12Q 1/68
IPC 8 full level
C12N 15/09 (2006.01); A61K 39/395 (2006.01); A61P 31/04 (2006.01); C07K 14/315 (2006.01); C07K 16/12 (2006.01); C12N 1/21 (2006.01); C12N 15/31 (2006.01); C12P 21/00 (2006.01); C12P 21/08 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/569 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP KR US)
A61K 39/09 (2013.01 - KR); A61P 31/04 (2018.01 - EP); C07K 14/315 (2013.01 - EP KR); C07K 14/3156 (2013.01 - EP); C07K 16/1275 (2013.01 - EP); C12N 15/11 (2013.01 - KR); A61K 38/00 (2013.01 - EP); A61K 39/00 (2013.01 - EP KR US); C07K 2317/34 (2013.01 - EP); C07K 2319/00 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9640928 A1 19961219; AP 9701163 A0 19980131; AR 003124 A1 19980708; AU 5682896 A 19961230; AU 700080 B2 19981217; BR 9609399 A 20010828; CA 2224015 A1 19961219; CN 1192241 A 19980902; CZ 394297 A3 19980415; EA 199800046 A1 19980625; EP 0832238 A1 19980401; HU P0600442 A2 20060828; HU P0600442 A3 20070328; IL 118329 A0 19960912; JP H11507214 A 19990629; KR 19990022742 A 19990325; NO 975752 D0 19971205; NO 975752 L 19980206; PL 323781 A1 19980427; SK 168497 A3 19980708; TR 199701537 T1 19980321
DOCDB simple family (application)
CA 9600322 W 19960517; AP 9701163 A 19960517; AR 10263196 A 19960520; AU 5682896 A 19960517; BR 9609399 A 19960517; CA 2224015 A 19960517; CN 96195891 A 19960517; CZ 394297 A 19960517; EA 199800046 A 19960517; EP 96914821 A 19960517; HU P0600442 A 19960517; IL 11832996 A 19960520; JP 50002697 A 19960517; KR 19970709184 A 19971208; NO 975752 A 19971205; PL 32378196 A 19960517; SK 168497 A 19960517; TR 9701537 T 19960517