EP 0833846 A4 19990714 - HUMAN G-PROTEIN COUPLED RECEPTOR (HETGQ23)
Title (en)
HUMAN G-PROTEIN COUPLED RECEPTOR (HETGQ23)
Title (de)
AN HUMANES G-PROTEIN GEKOPPELTER REZEPTOR
Title (fr)
RECEPTEUR COUPLE DE PROTEINES G HUMAINES (HETGQ23)
Publication
Application
Priority
- CA 2220978 A 19950605
- CN 95197932 A 19950605
- US 9507137 W 19950605
Abstract (en)
[origin: WO9639436A1] Human G-protein coupled receptor polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed were methods for utilizing such polypeptides for identifying antagonists and agonists to such polypeptides and methods of using the agonists and antagonists therapeutically to treat conditions related to the underexpression and overexpression of the G-protein coupled receptor polypeptides, respectively. Also disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.
IPC 1-7
IPC 8 full level
C07K 14/705 (2006.01); C07K 16/28 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01)
CPC (source: EP)
C07K 14/705 (2013.01); A61K 38/00 (2013.01); C12N 2799/026 (2013.01)
Citation (search report)
- [Y] WO 9307294 A1 19930415 - US HEALTH [US]
- [A] WO 9219723 A1 19921112 - UNIV BOSTON [US]
- [XY] DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002099777, Database accession no. U18405
- [X] DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002099778, Database accession no. F06566
- [A] OLIVEIRA L. ET AL.: "A common motif in G-protein-coupled seven transmembrane helix receptors", JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, vol. 7, no. 6, December 1993 (1993-12-01), pages 649 - 658, XP002050853
- [A] LEE N H ET AL: "Molecular biology of G-protein-coupled receptors", DRUG NEWS AND PERSPECTIVES, vol. 6, no. 7, September 1993 (1993-09-01), pages 488 - 497, XP000677175
- See references of WO 9639436A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9639436 A1 19961212; CA 2220978 A1 19961212; CN 1157410 C 20040714; CN 1193981 A 19980923; EP 0833846 A1 19980408; EP 0833846 A4 19990714
DOCDB simple family (application)
US 9507137 W 19950605; CA 2220978 A 19950605; CN 95197932 A 19950605; EP 95925238 A 19950605