EP 0833904 A1 19980408 - FIBROBLAST GROWTH FACTOR-14
Title (en)
FIBROBLAST GROWTH FACTOR-14
Title (de)
FIBROBLASTEN-WACHSTUMSFAKTOR-14
Title (fr)
FACTEUR DE CROISSANCE DES FIBROBLASTES 14
Publication
Application
Priority
- CA 2212992 A 19950605
- US 9506730 W 19950605
Abstract (en)
[origin: WO9639506A1] Disclosed is a human Fibroblast growth factor-14 polypeptide and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for promoting wound healing, for example as a result of burns and ulcers, to prevent neuronal damage due to/associated with stroke and promote neuronal growth, and to prevent skin aging and hair loss, to stimulate angiogenesis, mesodermal induction in early embryos and limb regeneration. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the coding sequence and alterations in the concentration of the polypeptides in a sample derived from a host are also disclosed.
IPC 1-7
IPC 8 full level
C07K 14/50 (2006.01); C12N 15/12 (2006.01); A61K 38/00 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C07K 14/50 (2013.01); A61K 38/00 (2013.01); A61K 48/00 (2013.01); C12N 2799/026 (2013.01)
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9639506 A1 19961212; AU 2653095 A 19961224; AU 702131 B2 19990211; CA 2212992 A1 19961212; EP 0833904 A1 19980408; EP 0833904 A4 20000517
DOCDB simple family (application)
US 9506730 W 19950605; AU 2653095 A 19950605; CA 2212992 A 19950605; EP 95921454 A 19950605