EP 0835448 A1 19980415 - MONOSPECIFIC ANTIBODIES AND METHODS USING THEM
Title (en)
MONOSPECIFIC ANTIBODIES AND METHODS USING THEM
Title (de)
MONOSPEZIFISCHE ANTIKÖRPER UND DIE VERWENDENDE VERFAHREN.
Title (fr)
ANTICORPS MONOSPECIFIQUES ET LEURS PROCEDES D'APPLICATION
Publication
Application
Priority
- US 9608438 W 19960603
- US 47699195 A 19950607
Abstract (en)
[origin: WO9641168A1] Monospecific antibodies are produced which are specific for the carboxyl-terminal region of human inducible nitric oxide synthase (hiNOS). These monospecific antibodies are used in an assay system to detect hiNOS. Elevations of hiNOS occur in hepatitis and inflammatory bowel disease, as well as numerous inflammatory diseases. The monospecific antibodies and the assay systems are used to quantitate hiNOS as a readout of hiNOS activity and to evaluate potential hiNOS modulators.
IPC 1-7
IPC 8 full level
C07K 16/40 (2006.01); C12N 9/02 (2006.01)
CPC (source: EP)
C07K 16/40 (2013.01); C12N 9/0075 (2013.01)
Citation (search report)
See references of WO 9641168A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9641168 A1 19961219; CA 2222436 A1 19961219; EP 0835448 A1 19980415
DOCDB simple family (application)
US 9608438 W 19960603; CA 2222436 A 19960603; EP 96919038 A 19960603