EP 0836616 A1 19980422 - MACROLIDES
Title (en)
MACROLIDES
Title (de)
MAKROLIDE
Title (fr)
MACROLIDES
Publication
Application
Priority
- EP 9602952 W 19960704
- GB 9513596 A 19950704
- GB 9515495 A 19950728
Abstract (en)
[origin: WO9702285A1] A novel class of macrolides in which i) positions 2 to 6 inclusive of the macrocyclic ring are provided by a piperidazinyl carboxylic acid residue; and/or ii) positions 7 to 9 inclusive of the macrocyclic ring are provided by an aromatic alpha -amino acid residue; and/or iii) positions 10 to 12 inclusive of the macrocyclic ring are provided by an aliphatic alpha -amino acid residue, preferably comprising two, or especially all three of the characteristic structural features i), ii) and iii), more especially a compound of formula (IX) is provided having immunosuppressant and anti-inflammatory properties and protected and ring-open forms thereof.
IPC 1-7
C07K 5/062; C07D 309/10; C07D 309/30; C07D 491/10; C12P 21/02; A61K 38/05; A61K 31/35; A61K 31/445; G01N 33/68
IPC 8 full level
A61K 31/495 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); C07D 309/10 (2006.01); C07D 309/30 (2006.01); C07D 491/10 (2006.01); C07D 498/08 (2006.01); C07D 519/00 (2006.01); C12P 21/02 (2006.01); C07K 5/06 (2006.01); C07K 5/062 (2006.01); C12N 1/20 (2006.01); A61K 38/00 (2006.01); C12R 1/465 (2006.01); C12R 1/645 (2006.01)
CPC (source: EP KR)
A61P 29/00 (2018.01 - EP); A61P 37/06 (2018.01 - EP); C07D 309/10 (2013.01 - EP); C07D 309/30 (2013.01 - EP); C07D 491/10 (2013.01 - EP); C07K 5/06017 (2013.01 - KR); C07K 5/06052 (2013.01 - EP); C12N 1/205 (2021.05 - EP); A61K 38/00 (2013.01 - EP); C12R 2001/465 (2021.05 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9702285 A1 19970123; AR 006514 A1 19990908; AU 6519396 A 19970205; AU 708004 B2 19990729; BR 9609324 A 19990525; CA 2224715 A1 19970123; CN 1193979 A 19980923; CO 4750713 A1 19990331; CZ 424297 A3 19980415; EP 0836616 A1 19980422; HU P9802320 A2 19990201; HU P9802320 A3 19990329; IL 122844 A0 19980816; JP H11509092 A 19990817; KR 19990028724 A 19990415; MX 9800217 A 19980731; NO 980016 D0 19980102; NO 980016 L 19980302; PL 324346 A1 19980525; SK 498 A3 19980708; TR 199800001 T1 19980421
DOCDB simple family (application)
EP 9602952 W 19960704; AR 10342796 A 19960703; AU 6519396 A 19960704; BR 9609324 A 19960704; CA 2224715 A 19960704; CN 96196487 A 19960704; CO 96034982 A 19960704; CZ 424297 A 19960704; EP 96924886 A 19960704; HU P9802320 A 19960704; IL 12284496 A 19960704; JP 50483297 A 19960704; KR 19980700022 A 19980105; MX 9800217 A 19980107; NO 980016 A 19980102; PL 32434696 A 19960704; SK 498 A 19960704; TR 9800001 T 19960704