EP 0836616 A1 19980422 - MACROLIDES
Title (en)
MACROLIDES
Title (de)
MAKROLIDE
Title (fr)
MACROLIDES
Publication
Application
Priority
- EP 9602952 W 19960704
- GB 9513596 A 19950704
- GB 9515495 A 19950728
Abstract (en)
[origin: WO9702285A1] A novel class of macrolides in which i) positions 2 to 6 inclusive of the macrocyclic ring are provided by a piperidazinyl carboxylic acid residue; and/or ii) positions 7 to 9 inclusive of the macrocyclic ring are provided by an aromatic alpha -amino acid residue; and/or iii) positions 10 to 12 inclusive of the macrocyclic ring are provided by an aliphatic alpha -amino acid residue, preferably comprising two, or especially all three of the characteristic structural features i), ii) and iii), more especially a compound of formula (IX) is provided having immunosuppressant and anti-inflammatory properties and protected and ring-open forms thereof.
IPC 1-7
C07K 5/062; C07D 309/10; C07D 309/30; C07D 491/10; C12P 21/02; A61K 38/05; A61K 31/35; A61K 31/445; G01N 33/68
IPC 8 full level
C12P 21/02 (2006.01); A61K 31/495 (2006.01); A61P 29/00 (2006.01); A61P 37/06 (2006.01); C07D 309/10 (2006.01); C07D 309/30 (2006.01); C07D 491/10 (2006.01); C07D 498/08 (2006.01); C07D 519/00 (2006.01); C07K 5/06 (2006.01); C07K 5/062 (2006.01); C12N 1/20 (2006.01); A61K 38/00 (2006.01); C12R 1/465 (2006.01); C12R 1/645 (2006.01)
CPC (source: EP KR)
A61P 29/00 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C07D 309/10 (2013.01 - EP); C07D 309/30 (2013.01 - EP); C07D 491/10 (2013.01 - EP); C07K 5/06017 (2013.01 - KR); C07K 5/06052 (2013.01 - EP); C12N 1/205 (2021.05 - EP); A61K 38/00 (2013.01 - EP); C12R 2001/465 (2021.05 - EP)
Citation (search report)
See references of WO 9702285A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9702285 A1 19970123; AR 006514 A1 19990908; AU 6519396 A 19970205; AU 708004 B2 19990729; BR 9609324 A 19990525; CA 2224715 A1 19970123; CN 1193979 A 19980923; CO 4750713 A1 19990331; CZ 424297 A3 19980415; EP 0836616 A1 19980422; HU P9802320 A2 19990201; HU P9802320 A3 19990329; IL 122844 A0 19980816; JP H11509092 A 19990817; KR 19990028724 A 19990415; MX 9800217 A 19980731; NO 980016 D0 19980102; NO 980016 L 19980302; PL 324346 A1 19980525; SK 498 A3 19980708; TR 199800001 T1 19980421
DOCDB simple family (application)
EP 9602952 W 19960704; AR 10342796 A 19960703; AU 6519396 A 19960704; BR 9609324 A 19960704; CA 2224715 A 19960704; CN 96196487 A 19960704; CO 96034982 A 19960704; CZ 424297 A 19960704; EP 96924886 A 19960704; HU P9802320 A 19960704; IL 12284496 A 19960704; JP 50483297 A 19960704; KR 19980700022 A 19980105; MX 9800217 A 19980107; NO 980016 A 19980102; PL 32434696 A 19960704; SK 498 A 19960704; TR 9800001 T 19960704