EP 0837690 A1 19980429 - A STABILIZED PHARMACEUTICAL FORMULATION COMPRISING A GROWTH HORMONE AND A PEPTIDE COMPRISING AT LEAST ONE BASIC AMINO ACID RESIDUE AND AT LEAST ONE ACID AMINO ACID RESIDUE
Title (en)
A STABILIZED PHARMACEUTICAL FORMULATION COMPRISING A GROWTH HORMONE AND A PEPTIDE COMPRISING AT LEAST ONE BASIC AMINO ACID RESIDUE AND AT LEAST ONE ACID AMINO ACID RESIDUE
Title (de)
EINE STABILISIERTE PHARMAZEUTISCHE FORMULIERUNG, DIE EIN WACHSTUMSHORMON UND EIN PEPTID MIT MINDESTENS EINER BASISCHEN AMINOSÄURE UND MINDESTENS EINER SAUREN AMINOSÄURE ENTHÄLT
Title (fr)
FORMULATION PHARMACEUTIQUE STABILISEE COMPORTANT UNE HORMONE DE CROISSANCE ET UN PEPTIDE CONTENANT AU MOINS UN RESTE D'ACIDE AMINE BASIQUE ET AU MOINS UN RESTE D'ACIDE AMINE ACIDE
Publication
Application
Priority
- DK 9600290 W 19960628
- US 88195 P 19950712
Abstract (en)
[origin: WO9702833A1] A pharmaceutical formulation comprising a growth hormone and a peptide comprising at least one basic amino acid residue and at least one acid amino acid residue as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.
IPC 1-7
IPC 8 full level
A61K 31/00 (2006.01); A61K 38/27 (2006.01); A61K 47/42 (2006.01); A61P 1/00 (2006.01); A61P 1/16 (2006.01); A61P 13/00 (2006.01); A61P 13/12 (2006.01); A61P 19/00 (2006.01); A61P 19/04 (2006.01); A61P 21/00 (2006.01)
CPC (source: EP KR)
A61K 38/27 (2013.01 - EP KR); A61P 1/00 (2018.01 - EP); A61P 1/16 (2018.01 - EP); A61P 13/00 (2018.01 - EP); A61P 13/12 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 19/04 (2018.01 - EP); A61P 21/00 (2018.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9702833 A1 19970130; AU 6353396 A 19970210; AU 699850 B2 19981217; BR 9609573 A 19990302; CA 2226553 A1 19970130; CN 1190896 A 19980819; CZ 6198 A3 19980617; EP 0837690 A1 19980429; HU P9802286 A2 19990201; HU P9802286 A3 19990628; IL 122519 A0 19980615; JP H11510483 A 19990914; KR 19990028908 A 19990415; MX 9800309 A 19980731; NO 980103 D0 19980109; NO 980103 L 19980109; PL 324386 A1 19980525; ZA 965367 B 19970123
DOCDB simple family (application)
DK 9600290 W 19960628; AU 6353396 A 19960628; BR 9609573 A 19960628; CA 2226553 A 19960628; CN 96195465 A 19960628; CZ 6198 A 19960628; EP 96922774 A 19960628; HU P9802286 A 19960628; IL 12251996 A 19960628; JP 50542297 A 19960628; KR 19980700210 A 19980112; MX 9800309 A 19960628; NO 980103 A 19980109; PL 32438696 A 19960628; ZA 965367 A 19960625