EP 0837868 A1 19980429 - NEW ANTICOAGULANTS
Title (en)
NEW ANTICOAGULANTS
Title (de)
ANTIKOAGULANTIEN.
Title (fr)
NOUVEAUX ANTICOAGULANTS
Publication
Application
Priority
- SE 9600859 W 19960628
- SE 9502656 A 19950719
- US 104095 P 19950629
Abstract (en)
[origin: WO9701568A1] The present invention relates to prevention and treatment of thromboembolic diseases by administration of a therapeutically effective dose of an active trisaccharide comprising an iduronic acid, a glucopyranosyl or glucopyranosylamine unit and a hexuronic acid selected from iduronic acid and glucuronic acid. The specific trisaccharides of the present invention have potent activity towards thrombin and also potentiate the inhibition of FXa, even if the trisaccharides lack sulfate groups. With the present invention, safe and potent anticoagulants with a potentially high oral absorption are achievable, due to the much smaller molecular size and presence of very few, if any, sulfate groups compared to presently available anticoagulants.
IPC 1-7
IPC 8 full level
C07H 3/06 (2006.01)
CPC (source: EP)
C07H 3/06 (2013.01)
Citation (search report)
See references of WO 9701568A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9701568 A1 19970116; AU 6324996 A 19970130; AU 706002 B2 19990603; EP 0837868 A1 19980429
DOCDB simple family (application)
SE 9600859 W 19960628; AU 6324996 A 19960628; EP 96922351 A 19960628