Global Patent Index - EP 0839049 A1

EP 0839049 A1 19980506 - A STABILIZED PHARMACEUTICAL FORMULATION COMPRISING A GROWTH HORMONE PRE-TREATED WITH ZINC AND OPTIONALLY LYSINE OR CALCIUM IONS

Title (en)

A STABILIZED PHARMACEUTICAL FORMULATION COMPRISING A GROWTH HORMONE PRE-TREATED WITH ZINC AND OPTIONALLY LYSINE OR CALCIUM IONS

Title (de)

EINE STABILISIERTE PHARMAZEUTISCHE FORMULIERUNG, DIE EIN WACHSTUMSHORMON ENTHÄLT, DAS MIT ZINKIONEN UND EVENTUELL MIT LYSIN ODER CALCIUMIONEN VORBEHANDELT IST

Title (fr)

FORMULATION PHARMACEUTIQUE STABILISEE COMPRENANT UNE HORMONE DE CROISSANCE PRE-TRAITEE AVEC DES IONS ZINC ET FACULTATIVEMENT LYSINE OU CALCIUM

Publication

EP 0839049 A1 19980506 (EN)

Application

EP 96922775 A 19960628

Priority

  • DK 9600293 W 19960628
  • US 119395 P 19950714

Abstract (en)

[origin: WO9703692A1] A pharmaceutical formulation comprising a growth hormone pre-treated with zinc and optionally lysine or calcium ions shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved formulation at ambient temperature.

IPC 1-7

A61K 38/27; A61K 33/30

IPC 8 full level

A61K 9/19 (2006.01); A61K 38/27 (2006.01); A61K 47/02 (2006.01); A61K 47/18 (2006.01)

CPC (source: EP KR US)

A61K 9/19 (2013.01 - EP); A61K 38/27 (2013.01 - EP KR); A61K 47/02 (2013.01 - EP); A61K 47/183 (2013.01 - EP US)

Citation (search report)

See references of WO 9703692A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9703692 A1 19970206; AU 6353496 A 19970218; AU 715997 B2 20000217; BR 9609741 A 19990316; CA 2226523 A1 19970206; CN 1190897 A 19980819; CZ 9498 A3 19980617; EP 0839049 A1 19980506; HU P9802287 A2 19990201; HU P9802287 A3 20001030; IL 122583 A0 19980615; JP H11509212 A 19990817; KR 19990028981 A 19990415; MX 9800358 A 19980731; NO 980155 D0 19980113; NO 980155 L 19980113; PL 324379 A1 19980525; ZA 965368 B 19970114

DOCDB simple family (application)

DK 9600293 W 19960628; AU 6353496 A 19960628; BR 9609741 A 19960628; CA 2226523 A 19960628; CN 96195537 A 19960628; CZ 9498 A 19960628; EP 96922775 A 19960628; HU P9802287 A 19960628; IL 12258396 A 19960628; JP 50617997 A 19960628; KR 19980700283 A 19980114; MX 9800358 A 19960628; NO 980155 A 19980113; PL 32437996 A 19960628; ZA 965368 A 19960625