EP 0839183 A1 19980506 - IMMORTALIZED EPITHELIAL TUMOR CELL
Title (en)
IMMORTALIZED EPITHELIAL TUMOR CELL
Title (de)
IMMORTALISIERTE EPITHELIALE TUMORZELLE
Title (fr)
CELLULE TUMORALE EPITHELIALE IMMORTALISEE
Publication
Application
Priority
- EP 96923904 A 19960624
- EP 9602747 W 19960624
- EP 95109860 A 19950623
Abstract (en)
[origin: WO9700946A1] The present invention relates to epithelial tumor cells with metastatic potential which have integrated in their genome or another replicative genetic element at least one externally introduced immortalizing oncogene and optionally at least one gene encoding an immunostimulatory factor which are expressed in such tumor cells. The invention further relates to antibodies which specifically recognize the epithelial tumor cells of the invention, to processes for the production of said tumor cells as well as pharmaceutical and diagnostic compositions comprising said tumor cells and antibodies, respectively. Finally the present invention relates to the use of the epithelial tumor cells and/or antibodies of the invention for the preparation of tumor vaccines and medicaments for the prophylaxis and/or treatment of cancer and/or the metastasis of cancer.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01); C12N 5/10 (2006.01); C12N 15/02 (2006.01); C12P 21/08 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP US)
A61K 39/001106 (2018.08 - EP US); A61K 39/001152 (2018.08 - EP US); A61K 39/001153 (2018.08 - EP US); A61K 39/001164 (2018.08 - EP US); A61P 35/00 (2018.01 - EP); C07K 16/30 (2013.01 - EP); A61K 2039/5152 (2013.01 - EP)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9700946 A1 19970109; AU 6415396 A 19970122; CA 2224797 A1 19970109; EP 0839183 A1 19980506; JP H11507834 A 19990713; NO 976036 D0 19971222; NO 976036 L 19980203
DOCDB simple family (application)
EP 9602747 W 19960624; AU 6415396 A 19960624; CA 2224797 A 19960624; EP 96923904 A 19960624; JP 50359097 A 19960624; NO 976036 A 19971222