EP 0840739 A4 20060201 - HIGH AFFINITY NUCLEIC ACID LIGANDS TO LECTINS
Title (en)
HIGH AFFINITY NUCLEIC ACID LIGANDS TO LECTINS
Title (de)
HOCHAFFINE NUKLEINSÄURELIGANDEN FÜR LECTINE
Title (fr)
LIGANDS D'ACIDE NUCLEIQUE A HAUTE AFFINITE POUR LES LECTINES
Publication
Application
Priority
- US 9609455 W 19960605
- US 47972495 A 19950607
- US 47225695 A 19950607
- US 47225595 A 19950607
- US 47782995 A 19950607
Abstract (en)
[origin: WO9640703A1] This invention discloses high-affinity oligonucleotide ligands to lectins, specifically nucleic acid ligands having the ability to bind to the lectins, wheat germ agglutinin, L-selectin, E-selectin and P-selectin. Also disclosed are the methods for obtaining such ligands.
IPC 1-7
C07H 19/00; C07H 21/02; C07H 21/04; C07H 21/00; C12Q 1/68; G01N 33/53
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/70 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 33/566 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 17/02 (2017.12); A61P 17/06 (2017.12); A61P 19/02 (2017.12); A61P 25/00 (2017.12); A61P 29/00 (2017.12); A61P 31/04 (2017.12); A61P 35/04 (2017.12); A61P 37/06 (2017.12); A61P 43/00 (2017.12); C12Q 1/6811 (2013.01); G01N 33/53 (2013.01); G01N 2333/4724 (2013.01); G01N 2333/7056 (2013.01); G01N 2333/96433 (2013.01)
Citation (search report)
- [X] WO 9409158 A1 19940428 - UNIV RESEARCH CORP [US]
- [X] US 5270163 A 19931214 - GOLD LARRY [US], et al
- [E] WO 9634876 A1 19961107 - NEXSTAR PHARMACEUTICALS INC [US], et al
- [T] US 2003059769 A1 20030327 - PARMA DAVID H [US], et al
- [T] US 6280932 B1 20010828 - PARMA DAVID H [US], et al
- [PX] HICKE B J ET AL: "DNA aptamers block L-selectin function in vivo. Inhibition of human lymphocyte trafficking in SCID mice.", THE JOURNAL OF CLINICAL INVESTIGATION. 15 DEC 1996, vol. 98, no. 12, 15 December 1996 (1996-12-15), pages 2688 - 2692, XP002294403, ISSN: 0021-9738
- [PX] O'CONNELL D ET AL: "Calcium-dependent oligonucleotide antagonists specific for L-selectin.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 11 JUN 1996, vol. 93, no. 12, 11 June 1996 (1996-06-11), pages 5883 - 5887, XP002294404, ISSN: 0027-8424
- See references of WO 9640703A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9640703 A1 19961219; AU 6450796 A 19961230; AU 725590 B2 20001012; CA 2223275 A1 19961219; EP 0840739 A1 19980513; EP 0840739 A4 20060201; JP 2009039126 A 20090226; JP H11507526 A 19990706
DOCDB simple family (application)
US 9609455 W 19960605; AU 6450796 A 19960605; CA 2223275 A 19960605; EP 96923232 A 19960605; JP 2008227400 A 20080904; JP 50177097 A 19960605