EP 0842143 B3 20090218 - 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES
Title (en)
2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES
Title (de)
2-(4-SUBSTITUIERTE)-BENZYLAMINO-2-METHYL-PROPANAMID-DERIVATE
Title (fr)
DERIVES DE 2-(4-SUBSTITUE)-BENZYLAMINO-2-METHYLPROPANAMIDE
Publication
Application
Priority
- EP 9602961 W 19960705
- GB 9515412 A 19950727
Abstract (en)
[origin: WO9705102A1] Novel 2-(4-substituted)-benzylamino-2-methyl-propanamides compounds, having CNS activity, of general formula (I) wherein: n is zero, 1, 2 or 3; X is -O-, -S-, -CH2- or -NH-; each of R and R1 independently is hydrogen, C1-C6 alkyl, halogen, hydroxy, C1-C4 alkoxy or trifluoromethyl; each of R2, R3 and R4 independently is hydrogen, C1-C6 alkyl or C3-C7 cycloalkyl; and the pharmaceutically acceptable salts thereof, are disclosed.
IPC 8 full level
A61K 31/00 (2006.01); A61K 31/16 (2006.01); C07C 237/06 (2006.01); A61K 31/165 (2006.01); A61P 25/16 (2006.01); A61P 25/20 (2006.01); A61P 25/24 (2006.01); C07C 231/12 (2006.01); C07C 321/30 (2006.01); C07C 323/32 (2006.01); C07C 323/36 (2006.01)
CPC (source: EP KR US)
A61K 31/16 (2013.01 - KR); A61P 25/00 (2018.01 - EP); A61P 25/08 (2018.01 - EP); A61P 25/16 (2018.01 - EP); A61P 25/20 (2018.01 - EP); A61P 25/24 (2018.01 - EP); A61P 25/28 (2018.01 - EP); A61P 27/00 (2018.01 - EP); C07C 237/06 (2013.01 - EP KR US); C07C 321/30 (2013.01 - KR); C07C 323/36 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI NL PT SE
Designated extension state (EPC)
SI
DOCDB simple family (publication)
WO 9705102 A1 19970213; AR 003469 A1 19980805; AT E202078 T1 20010615; AU 6418796 A 19970226; AU 711309 B2 19991007; AU 711309 C 19970226; BR 9609849 A 19990316; BR 9609849 B1 20100518; CA 2226894 A1 19970213; CA 2226894 C 20090331; CN 1085659 C 20020529; CN 1192199 A 19980902; DE 69613377 D1 20010719; DE 69613377 T2 20010920; DE 69613377 T4 20090813; DK 0842143 T3 20010723; DK 0842143 T5 20090602; EA 001322 B1 20010226; EA 199800170 A1 19980827; EP 0842143 A1 19980520; EP 0842143 B1 20010613; EP 0842143 B3 20090218; ES 2159749 T3 20011016; ES 2159749 T7 20090618; GB 9515412 D0 19950927; GR 3036559 T3 20011231; HU 227806 B1 20120328; HU P9900351 A2 19990628; HU P9900351 A3 19991129; IL 122705 A0 19980816; IL 122705 A 20010128; JP 2000500732 A 20000125; JP 4040089 B2 20080130; KR 100412747 B1 20040428; KR 19990035843 A 19990525; MX 9800718 A 19980430; NO 324273 B1 20070917; NO 980290 D0 19980122; NO 980290 L 19980122; NZ 313185 A 20000526; PL 184302 B1 20020930; PL 324639 A1 19980608; PT 842143 E 20011030; SI 0842143 T1 20010831; UA 44331 C2 20020215; US 5945454 A 19990831; ZA 965998 B 19970131
DOCDB simple family (application)
EP 9602961 W 19960705; AR 10375296 A 19960726; AT 96924888 T 19960705; AU 6418796 A 19960705; BR 9609849 A 19960705; CA 2226894 A 19960705; CN 96195901 A 19960705; DE 69613377 A 19960705; DE 69613377 T 19960705; DK 96924888 T 19960705; EA 199800170 A 19960705; EP 96924888 A 19960705; ES 96924888 T 19960705; GB 9515412 A 19950727; GR 20010401413 T 20010906; HU P9900351 A 19960705; IL 12270596 A 19960705; JP 50714797 A 19960705; KR 19980700503 A 19980123; MX 9800718 A 19960705; NO 980290 A 19980122; NZ 31318596 A 19960705; PL 32463996 A 19960705; PT 96924888 T 19960705; SI 9630307 T 19960705; UA 98021015 A 19960705; US 98149298 A 19980108; ZA 965998 A 19960715