EP 0843548 A2 19980527 - STABILIZED STEROID COMPOSITIONS
Title (en)
STABILIZED STEROID COMPOSITIONS
Title (de)
STABILISIERTE STEROIDHALTIGE MITTEL
Title (fr)
COMPOSITIONS STEROIDIENNES STABILISEES
Publication
Application
Priority
- US 9609651 W 19960605
- US 48533995 A 19950607
Abstract (en)
[origin: WO9640042A2] The degradation of triamcinolone acetonide in aqueous solutions is studied under accelerated storage conditions of 70 DEG C over the pH range 1-10. Trace level metal ions can markedly accelerate the oxidative degradation in neutral and basic solutions, but pH conditions and/or the inclusion of metal-sequestering agents, such as ethylenediamine tetra acetate (EDTA), in a preparation depresses the metal catalysis.
IPC 1-7
IPC 8 full level
A61K 31/58 (2006.01); A61K 47/02 (2006.01); A61K 47/18 (2006.01)
CPC (source: EP US)
A61K 31/58 (2013.01 - EP US); A61K 47/183 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9640042 A2 19961219; WO 9640042 A3 19970206; AU 6164196 A 19961230; BR 9608721 A 19991013; CA 2223385 A1 19961219; EP 0843548 A2 19980527; EP 0843548 A4 19981028; JP H11507359 A 19990629; MX 9709431 A 19981031
DOCDB simple family (application)
US 9609651 W 19960605; AU 6164196 A 19960605; BR 9608721 A 19960605; CA 2223385 A 19960605; EP 96919250 A 19960605; JP 50192597 A 19960605; MX 9709431 A 19971202