EP 0845990 A1 19980610 - NEW USE OF PREGNANE-DIONES AS ANALGESIC AGENTS
Title (en)
NEW USE OF PREGNANE-DIONES AS ANALGESIC AGENTS
Title (de)
NEUE VERWENDUNG VON PREGNANDIONEN ALS ANALGETIKA
Title (fr)
NOUVEL EMPLOI DE PREGNANES-DIONES COMME ANALGESIQUES
Publication
Application
Priority
- AU 9600531 W 19960823
- AU PN498095 A 19950823
Abstract (en)
[origin: WO9707807A1] The present invention provides: the new use of compounds of formula (II) wherein R<1> is H or Me, preferably H; R<2> is OH, preferably in alpha conformation; R<3> is H, or R<2> and R<3>, taken together, are O; R<4> is H or Me, preferably Me, and preferably in alpha conformation; R<5> is H; R<6> is H; or R<5> and R6, taken together, are O; R<7> is H or Me, preferably H; R<8> is H, Me or -CH2 O CO CH3. The present invention also provides a method of analgesia comprising administering an effective amount of a compound of formula (II) wherein R<1> est H or Me, preferably H; R<2> is OH, preferably in alpha conformation; R<3> is H, or R<2> and R<3>, taken together, are O; R<4> is H or Me, preferably Me, and preferably in alpha conformation; R<5> is H; R<6> is H; or R<5> and R<6>, taken together, are O; R<7> is H or Me, preferably H; R<8> is H, Me or -CH2 O CO CH3. The present invention also provides an analgesic composition comprising a compound of formula (II) wherein R<1> is H or Me, preferably H; R<2> is OH, preferably in alpha conformation; R<3> is H, or R<2> and R<3>, taken together, are O; R<4> is H or Me, preferably Me, and preferably in alpha conformation; R<5> is H; R<6> is H; or R<5> and R<6>, taken together, are O; R<7> is H or Me, preferably H; R<8> is H, Me or -CH2 O CO CH3 together with a pharmaceutically acceptable diluent.
IPC 1-7
IPC 8 full level
A61K 31/57 (2006.01); A61K 31/56 (2006.01); A61P 25/04 (2006.01)
CPC (source: EP)
A61K 31/56 (2013.01); A61K 31/57 (2013.01); A61K 31/573 (2013.01); A61P 25/04 (2017.12)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9707807 A1 19970306; AU PN498095 A0 19950914; EP 0845990 A1 19980610; EP 0845990 A4 20010214
DOCDB simple family (application)
AU 9600531 W 19960823; AU PN498095 A 19950823; EP 96927448 A 19960823