Global Patent Index - EP 0845994 A1

EP 0845994 A1 19980610 - COMBINED USE OF INTERLEUKIN-10 AND CYCLOSPORIN FOR IMMUNOSUPPRESSION THERAPY

Title (en)

COMBINED USE OF INTERLEUKIN-10 AND CYCLOSPORIN FOR IMMUNOSUPPRESSION THERAPY

Title (de)

KOMBINIERTE ANWENDUNG VON INTERLEUKIN-10 UND CYCLOSPORIN FÜR IMMUNOSUPPRESSIONTHERAPIE

Title (fr)

UTILISATION COMBINEE D'INTERLEUKINE-10 ET DE CYCLOSPORINE POUR UNE THERAPIE IMMUNOSUPPRESSIVE

Publication

EP 0845994 A1 19980610 (EN)

Application

EP 96928798 A 19960806

Priority

  • US 9612538 W 19960806
  • US 205795 P 19950809
  • US 61995896 A 19960320

Abstract (en)

[origin: WO9705896A1] A combination of interleukin-10 and cyclosporin is used to suppress graft-versus-host disease, autoimmune diseases and tissue/graft rejection. It has been discovered that administration of a combination of interleukin-10 and cyclosporin causes synergistic suppression of T cell proliferation. Concurrent use of both agents avoids the toxicity associated with higher doses of cyclosporin.

IPC 1-7

A61K 38/20

IPC 8 full level

A61K 38/00 (2006.01); A61K 31/00 (2006.01); A61K 38/20 (2006.01); A61P 37/00 (2006.01); A61P 37/06 (2006.01)

CPC (source: EP)

A61K 38/2066 (2013.01); A61P 37/00 (2017.12); A61P 37/06 (2017.12)

Citation (search report)

See references of WO 9705896A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9705896 A1 19970220; AU 6842296 A 19970305; AU 712606 B2 19991111; CA 2228379 A1 19970220; EP 0845994 A1 19980610; JP H11510806 A 19990921

DOCDB simple family (application)

US 9612538 W 19960806; AU 6842296 A 19960806; CA 2228379 A 19960806; EP 96928798 A 19960806; JP 50851597 A 19960806