EP 0846120 A1 19980610 - LOW MOLECULAR WEIGHT BICYCLIC-AREA TYPE THROMBIN INHIBITORS
Title (en)
LOW MOLECULAR WEIGHT BICYCLIC-AREA TYPE THROMBIN INHIBITORS
Title (de)
NIEDERMOLEKULARE BIZYKLISCHE HARNSTOFFTYP THROMBIN INHIBITOREN
Title (fr)
INHIBITEURS DE THROMBINE BICYCLIQUES DE TYPE UREE ET DE FAIBLE POIDS MOLECULAIRE
Publication
Application
Priority
- CA 9600318 W 19960522
- GB 9510264 A 19950522
Abstract (en)
[origin: WO9637497A1] This invention relates to heterocyclic inhibitors of the enzyme thrombin, their preparation, and pharmaceutical compositions thereof having general formula (I), wherein X, R2, R3, R4, R6, R7 and R8 are as defined herein. Also, the invention relates to the use of such compounds and compositions as anticoagulants and as agents for the treatment and prophylaxis or thrombotic disorders such as venous thrombosis, pulmonary embolism and arterial thrombosis resulting in acute ischemic events such as myocardial infarction or cerebral infarction.
IPC 1-7
IPC 8 full level
A61K 31/425 (2006.01); A61K 31/505 (2006.01); A61P 7/02 (2006.01); C07D 513/04 (2006.01)
CPC (source: EP)
A61P 7/02 (2017.12); C07D 513/04 (2013.01)
Citation (search report)
See references of WO 9637497A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9637497 A1 19961128; AU 5682596 A 19961211; CA 2218816 A1 19961128; EP 0846120 A1 19980610; GB 9510264 D0 19950719; JP H11505260 A 19990518; ZA 964090 B 19970513
DOCDB simple family (application)
CA 9600318 W 19960522; AU 5682596 A 19960522; CA 2218816 A 19960522; EP 96914817 A 19960522; GB 9510264 A 19950522; JP 53522196 A 19960522; ZA 964090 A 19960522